Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 4/20 | 0.41 |
| ▸ | HTR7 | P34969 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1015099 | 0.84 | KMT2A (0.56) | CA2ALDH1A1MAPTPPARGPPARD | |
| SCHEMBL31285935 | 0.82 | TTR (0.60) | CA2ALDH1A1MAPTPPARGPPARD | |
| SCHEMBL252910 | 0.82 | PTGS2 (0.52) | CA2ALDH1A1MAPTTTRL3MBTL1 | |
| SCHEMBL2974160 | 0.82 | TTR (0.60) | CA2ALDH1A1MAPTPPARGPPARD | |
| SCHEMBL638384 | 0.81 | CA2 (0.68) | CA2ALDH1A1MAPTPPARGPPARD | |
| SCHEMBL1548047 | 0.80 | NPC1 (0.53) | CA2ALDH1A1MAPTTTRL3MBTL1 | |
| SCHEMBL10349093 | 0.80 | CA2 (0.45) | CA2ALDH1A1MAPTPPARGPPARD | |
| SCHEMBL29673212 | 0.80 | CSNK2A1 (0.51) | CA2ALDH1A1MAPTTTRL3MBTL1 | |
| SCHEMBL30029152 | 0.80 | ALDH1A1 (0.47) | CA2ALDH1A1MAPTTTRL3MBTL1 | |
| SCHEMBL7668780 | 0.80 | ALDH1A1 (0.47) | CA2ALDH1A1MAPTTTRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001030745-A1 | ANTHRANILIC ACID DERIVATIVES AS INHIBITORS OF THE CGMP-PHOSPHODIESTERASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-03 | — | — | WO | disclosed |