Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7368292 | 0.82 | ALDH1A1 (0.44) | ALDH1A1KMT2AMAPK1TDP1LMNA | |
| SCHEMBL7368288 | 0.82 | ALDH1A1 (0.44) | ALDH1A1KMT2AMAPK1TDP1LMNA | |
| SCHEMBL7377422 | 0.80 | SNCA (0.52) | ALDH1A1KMT2AMAPK1TDP1LMNA | |
| SCHEMBL7368764 | 0.80 | ALDH1A1 (0.46) | ALDH1A1KMT2AMAPK1TDP1LMNA | |
| SCHEMBL7337134 | 0.78 | ALDH1A1 (0.49) | ALDH1A1KMT2AMAPK1TDP1LMNA | |
| SCHEMBL7376368 | 0.77 | ALDH1A1 (0.48) | ALDH1A1KMT2AMAPK1TDP1LMNA | |
| SCHEMBL7368736 | 0.75 | KMT2A (0.46) | ALDH1A1KMT2AMAPK1TDP1LMNA | |
| SCHEMBL7377964 | 0.74 | POLB (0.56) | ALDH1A1KMT2AMAPK1LMNAMAPT | |
| SCHEMBL7374952 | 0.74 | MAPT (0.42) | ALDH1A1KMT2AMAPTCRHBPCRHR2 | |
| SCHEMBL7374954 | 0.74 | MAPT (0.42) | ALDH1A1KMT2AMAPTCRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |