Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 8/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7368292 | 1.00 | ALDH1A1 (0.44) | ALDH1A1KMT2ATDP1MAPK1MAPT | |
| SCHEMBL7370181 | 0.87 | L3MBTL1 (0.38) | ALDH1A1TDP1MAPK1LMNAL3MBTL1 | |
| SCHEMBL7368764 | 0.82 | ALDH1A1 (0.46) | ALDH1A1KMT2ATDP1MAPK1MAPT | |
| SCHEMBL7368291 | 0.82 | ALDH1A1 (0.43) | ALDH1A1KMT2ATDP1MAPK1MAPT | |
| SCHEMBL7377424 | 0.81 | SNCA (0.51) | ALDH1A1KMT2ATDP1MAPK1MAPT | |
| SCHEMBL7377419 | 0.81 | SNCA (0.51) | ALDH1A1KMT2ATDP1MAPK1MAPT | |
| SCHEMBL7337134 | 0.81 | ALDH1A1 (0.49) | ALDH1A1KMT2ATDP1MAPK1MAPT | |
| SCHEMBL7373216 | 0.79 | KMT2A (0.53) | ALDH1A1KMT2ATDP1MAPK1MAPT | |
| SCHEMBL7378630 | 0.78 | AVPR2 (0.41) | ALDH1A1KMT2AMAPK1MAPTLMNA | |
| SCHEMBL7378634 | 0.78 | AVPR2 (0.41) | ALDH1A1KMT2AMAPK1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |