Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.55 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | CCR3 | P51677 | 6/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7359608 | 0.84 | F2 (0.68) | MGLLF2CCR3MEN1KMT2A | |
| SCHEMBL14559801 | 0.83 | FAAH (0.57) | MGLLKCNH2HRH3FAAHL3MBTL1 | |
| SCHEMBL7359604 | 0.82 | MGLL (0.53) | MGLLCCR3KCNH2HRH3FAAH | |
| SCHEMBL7233081 | 0.74 | HTT (0.65) | MGLLCCR3MEN1KMT2A | |
| SCHEMBL1063488 | 0.74 | MGLL (0.62) | MGLLF2MEN1KMT2A | |
| SCHEMBL7370469 | 0.73 | TP53 (0.59) | MGLLCCR3MEN1KMT2A | |
| SCHEMBL6397917 | 0.73 | MGLL (0.66) | MGLLCCR3FAAHHTR2A | |
| SCHEMBL7167258 | 0.72 | KDM4E (0.45) | L3MBTL1MEN1KMT2A | |
| SCHEMBL7360128 | 0.72 | F2 (0.69) | MGLLF2CCR3MEN1KMT2A | |
| SCHEMBL14570741 | 0.71 | MGLL (0.56) | MGLLF2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6043257-A | ANTICOAGULANT; PYRIDINE SUBSTITUTED INDAZOLE COMPOUND | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-03-28 | — | — | US | disclosed |
| EP-0960102-A1 | AMIDINOINDOLES, AMIDINOAZOLES, AND ANALOGS THEREOF AS INHIBITORS OF FACTOR Xa AND OF THROMBIN | Du Pont Pharmaceuticals Company (US) | 1999-12-01 | — | — | EP | disclosed |
| US-5886191-A | ANTICOAGULANTS | DUPONT PHARMACEUTICALS COMPANY (US) | 1999-03-23 | — | — | US | disclosed |
| WO-1998001428-A1 | AMIDINOINDOLES, AMIDINOAZOLES, AND ANALOGS THEREOF AS INHIBITORS OF FACTOR Xa AND OF THROMBIN | DU PONT PHARMACEUTICALS COMPANY (US) | 1998-01-15 | — | — | WO | disclosed |