Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 4/20 | 0.58 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7371083 | 0.91 | HTT (0.56) | L3MBTL1NPC1RAB9ACHRNB2CHRNB4 | |
| SCHEMBL7376298 | 0.91 | L3MBTL1 (0.48) | HSD17B1HSD17B2L3MBTL1NPC1RAB9A | |
| SCHEMBL7378335 | 0.90 | CHRNB2 (0.52) | L3MBTL1NPC1RAB9ACHRNB2CHRNB4 | |
| SCHEMBL7369984 | 0.89 | GAA (0.57) | HSD17B1HSD17B2L3MBTL1NPC1RAB9A | |
| SCHEMBL7517678 | 0.85 | NPC1 (0.47) | L3MBTL1NPC1RAB9ACHRNB2CHRNB4 | |
| SCHEMBL7376778 | 0.85 | NPC1 (0.51) | L3MBTL1NPC1RAB9ACHRNB2CHRNB4 | |
| SCHEMBL7375535 | 0.84 | L3MBTL1 (0.50) | L3MBTL1NPC1RAB9ACHRNB2CHRNB4 | |
| SCHEMBL7374859 | 0.84 | NAMPT (0.52) | L3MBTL1NPC1RAB9ACHRNB2CHRNB4 | |
| SCHEMBL7375099 | 0.84 | NPC1 (0.50) | L3MBTL1NPC1RAB9ACHRNB2CHRNB4 | |
| SCHEMBL7367644 | 0.83 | GAA (0.64) | NPC1RAB9AKMT2ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |