Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | PAM | P19021 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PRKCA | P17252 | 1/20 | 0.47 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.47 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.47 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20751605 | 1.00 | DGKA (0.62) | DGKATSHRPAMMAPTLMNA | |
| SCHEMBL20751579 | 1.00 | DGKA (0.62) | DGKATSHRPAMMAPTLMNA | |
| SCHEMBL20751585 | 1.00 | DGKA (0.62) | DGKATSHRPAMMAPTLMNA | |
| SCHEMBL3115661 | 0.98 | DGKA (0.59) | DGKATSHRPAMMAPTLMNA | |
| SCHEMBL7989709 | 0.92 | DGKA (0.50) | DGKATSHRPAMMAPTLMNA | |
| SCHEMBL16351435 | 0.84 | DGKA (0.67) | DGKATSHRPAMMAPTLMNA | |
| SCHEMBL9276669 | 0.84 | DGKA (0.67) | DGKATSHRPAMMAPTLMNA | |
| SCHEMBL16351434 | 0.84 | DGKA (0.67) | DGKATSHRPAMMAPTLMNA | |
| SCHEMBL844443 | 0.84 | ALDH1A1 (0.48) | DGKATSHRPAMMAPTLMNA | |
| SCHEMBL11226211 | 0.83 | DGKA (0.78) | DGKATSHRPAMMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0970071-A1 | 2-PEPERAZINONE-1-ACETIC ACID DERIVATIVES AND THEIR USE | Takeda Chemical Industries, Ltd. (JP) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998039324-A1 | 2-PEPERAZINONE-1-ACETIC ACID DERIVATIVES AND THEIR USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-11 | — | — | WO | disclosed |