SCHEMBL7989709

SCHEMBL7989709

CCCCC(=O)OCOC=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.50
TSHR P16473 2/20 0.47
PAM P19021 2/20 0.46
MAPT P10636 2/20 0.43
LMNA P02545 2/20 0.42
ALDH1A1 P00352 2/20 0.42
DNM1 Q05193 1/20 0.42
CYP3A4 P08684 1/20 0.42
ATM Q13315 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
CYP1A2 P05177 1/20 0.41
KDM4E B2RXH2 1/20 0.41
DUSP3 P51452 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
MGLL Q99685 1/20 0.40
THRB P10828 1/20 0.39
CNR1 P21554 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3115661 0.94 DGKA (0.59) DGKATSHRPAMMAPTLMNA
SCHEMBL7368460 0.92 DGKA (0.62) DGKATSHRPAMMAPTLMNA
SCHEMBL20751605 0.92 DGKA (0.62) DGKATSHRPAMMAPTLMNA
SCHEMBL20751579 0.92 DGKA (0.62) DGKATSHRPAMMAPTLMNA
SCHEMBL20751585 0.92 DGKA (0.62) DGKATSHRPAMMAPTLMNA
SCHEMBL844443 0.87 ALDH1A1 (0.48) DGKATSHRPAMMAPTLMNA
SCHEMBL10099629 0.82 DGKA (0.62) DGKATSHRPAMMAPTLMNA
SCHEMBL9277257 0.79 DGKA (0.71) DGKATSHRPAMMAPTLMNA
SCHEMBL845081 0.78
SCHEMBL25908011 0.77 EPHX2 (0.37) DGKATSHRPAMMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023210623-A1 HALOALKYL SULFONE ANILIDE COMPOUND AND HERBICIDE CONTAINING SAME 株式会社エス・ディー・エス バイオテック 2023-11-02 WO disclosed
US-6265418-B1 ANTICOAGULANTS UBE INDUSTRIES, LTD. (JP) 2001-07-24 US disclosed
EP-1020467-A1 N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF UBE INDUSTRIES LIMITED (JP) 2000-07-19 EP disclosed
US-5614519-A (1-(2,3 or 4-N-morpholinoalkyl)-imidazol-4-yl)-benizimidazol-1-yl-methyl]-biphenyls useful as angiotensin-II antagonists KARL THOMAE GMBH (DE) 1997-03-25 US disclosed
US-5602127-A ADMINISTERING TO TREAT HYPERTENSION KARL THOMAE GMBH (DE) 1997-02-11 US disclosed
US-5594003-A HYPOTENSIVE AGENTS DR. KARL THOMAE GMBH (DE) 1997-01-14 US disclosed
US-5591762-A HYPOTENSIVE AGENTS DR. KARL THOMAE GMBH (DE) 1997-01-07 US disclosed
US-5482948-A Pyridyl derivatives and pharmaceutical compositions comprising these compounds DR. KARL THOMAE GMBH (DE) 1996-01-09 US disclosed
US-5459147-A Angeotensin-antagonistic effects; hypotensive, antiischemic, and antidiabetic agents, treating glaucoma DR. KARL THOMAE GMBH (DE) 1995-10-17 US disclosed