Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 3/20 | 0.36 |
| ▸ | F10 | P00742 | 4/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.33 |
| ▸ | SCN4A | P35499 | 1/20 | 0.33 |
| ▸ | MLLT1 | Q03111 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 3/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.32 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7374728 | 0.90 | KIF18A (0.34) | ROCK2F10MLLT1CYP2C9KIF18A | |
| SCHEMBL7373208 | 0.89 | MAPT (0.38) | ROCK2F10MAPT | |
| SCHEMBL6171243 | 0.83 | GPR119 (0.36) | F10MAPTSMN1; SMN2 | |
| SCHEMBL7369945 | 0.82 | F10 (0.44) | F10 | |
| SCHEMBL7372042 | 0.82 | F10 (0.38) | ROCK2F10SCN3ASCN4AMLLT1 | |
| SCHEMBL7372221 | 0.78 | F10 (0.39) | F10 | |
| SCHEMBL6168826 | 0.78 | RXFP2 (0.46) | F10 | |
| SCHEMBL7369526 | 0.76 | F10 (0.41) | F10JAK2KIF18A | |
| SCHEMBL7374706 | 0.75 | F10 (0.46) | F10MAPTROCK1 | |
| SCHEMBL7372754 | 0.74 | F10 (0.42) | F10JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019045-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2002-07-03 | — | — | EP | disclosed |
| EP-1019045-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-1999000128-A9 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 1999-08-05 | — | — | WO | disclosed |
| WO-1999000128-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1999-01-07 | — | — | WO | disclosed |