Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 8/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL242653 | 0.86 | KMT2A (0.74) | ALDH1A1KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL10522426 | 0.84 | ALDH1A1 (0.77) | ALDH1A1KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL4911112 | 0.83 | LMNA (0.55) | ALDH1A1KMT2AMEN1RAB9ALMNA | |
| SCHEMBL18956877 | 0.80 | ALDH1A1 (0.59) | ALDH1A1KMT2AMEN1RAB9ANPC1 | |
| Acetic Acid SCHEMBL4766215 | 0.79 | ALDH1A1 (0.67) | ALDH1A1KMT2AMEN1RAB9ANPC1 | |
| Acetic Acid SCHEMBL4766209 | 0.79 | ALDH1A1 (0.67) | ALDH1A1KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL8099661 | 0.79 | MEN1 (0.66) | ALDH1A1KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL25309429 | 0.79 | KMT2A (0.65) | ALDH1A1KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL5025726 | 0.79 | MEN1 (0.65) | ALDH1A1KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL8875848 | 0.79 | ALDH1A1 (0.66) | ALDH1A1KMT2AMEN1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380218-B1 | FOR THERAPY OF RESPIRATORY, ALLERGIC, AND INFLAMMATORY DISORDERS COMPRISING ASTHMA, CHRONIC OBSTRUCTIVE PULMONARY DISEASE, ACUTE RESPIRATORY DISEASE SYNDROME, PULMONARY HYPERSENSITIVITY, AND ALLERGIC RHINITIS IN A MAMMAL | PFIZER INC | 2002-04-30 | — | — | US | disclosed |
| EP-0971894-A1 | NICOTINAMIDE DERIVATIVES | Pfizer Products Inc. (US) | 2000-01-19 | — | — | EP | disclosed |
| WO-1998045268-A1 | NICOTINAMIDE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 1998-10-15 | — | — | WO | disclosed |