Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.74 |
| ▸ | MEN1 | O00255 | 5/20 | 0.74 |
| ▸ | RAB9A | P51151 | 4/20 | 0.74 |
| ▸ | NPC1 | O15118 | 3/20 | 0.74 |
| ▸ | ATM | Q13315 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | LTA4H | P09960 | 1/20 | 0.59 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL4766209 | 0.93 | ALDH1A1 (0.67) | KMT2AMEN1RAB9ANPC1ATM | |
| SCHEMBL8099661 | 0.93 | MEN1 (0.66) | KMT2AMEN1RAB9ANPC1ATM | |
| Acetic Acid SCHEMBL4766215 | 0.93 | ALDH1A1 (0.67) | KMT2AMEN1RAB9ANPC1ATM | |
| SCHEMBL10522426 | 0.88 | ALDH1A1 (0.77) | KMT2AMEN1RAB9ANPC1ATM | |
| SCHEMBL25309429 | 0.86 | KMT2A (0.65) | KMT2AMEN1RAB9ANPC1ATM | |
| SCHEMBL7368692 | 0.86 | ALDH1A1 (0.61) | KMT2AMEN1RAB9ANPC1ATM | |
| SCHEMBL3597296 | 0.86 | ALDH1A1 (0.66) | KMT2AMEN1RAB9ANPC1ATM | |
| SCHEMBL8875848 | 0.86 | ALDH1A1 (0.66) | KMT2AMEN1RAB9ANPC1ATM | |
| SCHEMBL5025726 | 0.86 | MEN1 (0.65) | KMT2AMEN1RAB9ANPC1ATM | |
| SCHEMBL27445845 | 0.82 | ALDH1A1 (0.57) | KMT2AMEN1RAB9ANPC1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102112448-B | DAA-pyridine as peripheral benzodiazepine receptor ligand for diagnostic imaging and pharmaceutical treatment | BAYER SCHERING PHARMA AG | 2014-08-06 | — | — | CN | disclosed |
| EP-2321279-B1 | DAA-PYRIDINE AS PERIPHERAL BENZODIAZEPINE RECEPTOR LIGAND FOR DIAGNOSTIC IMAGING AND PHARMACEUTICAL TREATMENT | PIRAMAL IMAGING SA (CH) | 2014-07-02 | — | — | EP | disclosed |
| EP-2408451-A2 | RADIOLABELLED PYRIDINYL DERIVATIVES FOR IN-VIVO IMAGING | GE Healthcare UK Limited (GB) | 2012-01-25 | — | — | EP | disclosed |
| US-20120003154-A1 | ARYLOXYANILIDE DERIVATIVES | GE HEALTHCARE LIMITED (GB) | 2012-01-05 | — | — | US | disclosed |
| US-20120003154-A1 | ARYLOXYANILIDE DERIVATIVES | GE HEALTHCARE LIMITED (GB) | 2012-01-05 | — | — | US | disclosed |
| US-20110200535-A1 | DAA-PYRIDINE AS PERIPHERAL BENZODIAZEPINE RECEPTOR LIGAND FOR DIAGNOSTIC IMAGING AND PHARMACEUTICAL TREATMENT | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-08-18 | — | — | US | disclosed |
| US-20110200535-A1 | DAA-PYRIDINE AS PERIPHERAL BENZODIAZEPINE RECEPTOR LIGAND FOR DIAGNOSTIC IMAGING AND PHARMACEUTICAL TREATMENT | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-08-18 | — | — | US | disclosed |
| CN-102112448-A | DAA-pyridine as peripheral benzodiazepine receptor ligand for diagnostic imaging and pharmaceutical treatment | BAYER SCHERING PHARMA AG | 2011-06-29 | — | — | CN | disclosed |
| EP-2321279-A1 | DAA-PYRIDINE AS PERIPHERAL BENZODIAZEPINE RECEPTOR LIGAND FOR DIAGNOSTIC IMAGING AND PHARMACEUTICAL TREATMENT | Bayer Schering Pharma Aktiengesellschaft (DE) | 2011-05-18 | — | — | EP | disclosed |
| WO-2010106166-A2 | ARYLOXYANILIDE DERIVATIVES | GE HEALTHCARE LIMITED (GB) | 2010-09-23 | — | — | WO | disclosed |
| WO-2003050117-A1 | SULFONAMIDO SUBSTITUTED IMIDAZOPYRIDINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-06-19 | — | — | WO | disclosed |
| WO-2003050119-A2 | UREA SUBSTITUTED IMIDAZOPYRIDINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-06-19 | — | — | WO | disclosed |
| US-6545017-B1 | Inducing cytokine biosynthesis; treating a viral and neoplastic diseases | 3M INNOVATIVE PROPERTIES COMPANY | 2003-04-08 | — | — | US | disclosed |
| US-6545016-B1 | Inducing cytokine biosynthesis; treating a viral and neoplastic diseases | 3M INNOVATIVE PROPERTIES COMPANY | 2003-04-08 | — | — | US | disclosed |
| US-6525064-B1 | Immune response modifiers; can induce the biosynthesis of various cytokines; | 3M INNOVATIVE PROPERTIES COMPANY | 2003-02-25 | — | — | US | disclosed |
| US-20020107262-A1 | SUBSTITUTED IMIDAZOPYRIDINES | 3M INNOVATIVE PROPERTIES COMPANY | 2002-08-08 | — | — | US | disclosed |
| WO-2002046194-A2 | SUBSTITUTED IMIDAZOPYRIDINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2002-06-13 | — | — | WO | disclosed |
| US-5977146-A | Pyridylcarbamates, process and intermediates for their preparation, and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-02 | — | — | US | disclosed |
| EP-0874825-A1 | PYRIDYL CARBAMATES, PROCESS AND INTERMEDIATES FOR THE PREPARATION AND USE THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 1998-11-04 | — | — | EP | disclosed |
| WO-1997021679-A1 | PYRIDYL CARBAMATES, PROCESS AND INTERMEDIATES FOR THE PREPARATION AND USE THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 1997-06-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110200535-A1 | DAA-PYRIDINE AS PERIPHERAL BENZODIAZEPINE RECEPTOR LIGAND FOR DIAGNOSTIC IMAGING AND PHARMACEUTICAL TREATMENT | GABRA6, GABRA4, GABRA1 | KMT2A 702/4885MEN1 1074/4885RAB9A 1848/4885 |
| US-20020107262-A1 | SUBSTITUTED IMIDAZOPYRIDINES | IRF3, IFNG, EIF2AK2 | KMT2A 2348/4885MEN1 2807/4885RAB9A 1655/4885 |
| US-20120003154-A1 | ARYLOXYANILIDE DERIVATIVES | GABBR1, GABRA4, CNR1 | KMT2A 2012/4885MEN1 3626/4885RAB9A 3285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.