Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | AVPR2 | P30518 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7368726 | 1.00 | PPARD (0.42) | PPARDCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7377226 | 0.97 | PPARD (0.45) | PPARDCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7377221 | 0.97 | PPARD (0.45) | PPARDCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7375232 | 0.89 | POLB (0.40) | PPARDCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7375229 | 0.89 | POLB (0.40) | PPARDCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7375748 | 0.89 | POLB (0.40) | PPARDCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7370825 | 0.86 | CHRNB2 (0.38) | CHRNB2CHRNB4CHRNA3CHRNA4POLB | |
| SCHEMBL7370821 | 0.85 | GAA (0.39) | CHRNB2CHRNB4CHRNA3CHRNA4POLB | |
| SCHEMBL7370827 | 0.85 | GAA (0.39) | CHRNB2CHRNB4CHRNA3CHRNA4POLB | |
| SCHEMBL7748312 | 0.85 | AVPR2 (0.41) | AVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |
| EP-0757670-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |