Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP7 | P09237 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | ECE1 | P42892 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7378250 | 0.97 | CA1 (0.46) | CA1CA2FAAHMMP1MMP7 | |
| SCHEMBL7376546 | 0.94 | CA2 (0.49) | CA1CA2FAAHMMP1MMP7 | |
| SCHEMBL7370650 | 0.92 | TDP1 (0.40) | CA1CA2FAAHMMP1TDP1 | |
| SCHEMBL7371375 | 0.89 | TSHR (0.41) | CA1CA2FAAHMMP1MMP7 | |
| SCHEMBL4912359 | 0.85 | TDP1 (0.46) | CA1CA2FAAHTDP1TSHR | |
| SCHEMBL8488430 | 0.80 | TSHR (0.41) | CA1CA2FAAHMMP1MMP7 | |
| SCHEMBL7374314 | 0.79 | TDP1 (0.39) | CA1CA2MMP1TDP1TSHR | |
| SCHEMBL8426506 | 0.79 | CA2 (0.58) | CA1CA2FAAH | |
| SCHEMBL7377886 | 0.76 | CYP2D6 (0.39) | CA1CA2MMP1TDP1TSHR | |
| SCHEMBL8426469 | 0.74 | ALDH1A1 (0.37) | MMP1TSHRALDH1A1METAP1METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1102752-A1 | SUCCINOYLAMINO LACTAMS AS INHIBITORS OF A BETA PROTEIN PRODUCTION | Du Pont Pharmaceuticals Company (US) | 2001-05-30 | — | — | EP | claimed |
| WO-2000007995-A1 | SUCCINOYLAMINO LACTAMS AS INHIBITORS OF Aβ PROTEIN PRODUCTION | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-02-17 | — | — | WO | claimed |
| EP-1102752-A1 | SUCCINOYLAMINO LACTAMS AS INHIBITORS OF A BETA PROTEIN PRODUCTION | Du Pont Pharmaceuticals Company (US) | 2001-05-30 | — | — | EP | disclosed |
| WO-2000007995-A1 | SUCCINOYLAMINO LACTAMS AS INHIBITORS OF Aβ PROTEIN PRODUCTION | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-02-17 | — | — | WO | disclosed |