SCHEMBL736885

SCHEMBL736885

C=C(C)C(=O)OC(OC)([SiH2]C)C(C)OC

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2854151 0.78 ALDH1A1 (0.38) ALDH1A1TSHR
SCHEMBL2248758 0.75 ALDH1A1 (0.41) ALDH1A1TSHR
SCHEMBL28593155 0.74 ALDH1A1 (0.31) ALDH1A1
SCHEMBL16161317 0.74 ALDH1A1 (0.40) ALDH1A1TSHR
SCHEMBL10941495 0.73 ALDH1A1 (0.36) ALDH1A1TSHR
SCHEMBL5493247 0.72 TSHR (0.34) TSHR
Methacrylic Acid SCHEMBL28495795 0.71 ALDH1A1 (0.38) ALDH1A1TSHR
SCHEMBL29056445 0.70 TSHR (0.43) ALDH1A1TSHR
SCHEMBL25371409 0.68 TSHR (0.35) ALDH1A1TSHR
SCHEMBL4348738 0.66 ALDH1A1 (0.42) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8709543-B2 Hydroxyl-terminated thiocarbonate containing compounds, polymers, and copolymers, and polyurethanes and urethane acrylics made therefrom LUBRIZOL ADVANCED MATERIALS, INC. (US) 2014-04-29 US claimed
EP-1773905-B1 HYDROXYL-TERMINATED THIOCARBONATE CONTAINING COMPOUNDS, POLYMERS, AND COPOLYMERS, AND POLYURETHANES AND URETHANE ACRYLICS MADE THEREFROM LUBRIZOL ADVANCED MAT INC (US) 2013-10-09 EP claimed
US-8492576-B2 Hydroxyl-terminated thiocarbonate containing compounds, polymers, and copolymers, and polyurethanes and urethane acrylics made therefrom LUBRIZOL ADVANCED MATERIALS, INC. (US) 2013-07-23 US claimed
US-20120171914-A1 Hydroxyl-Terminated Thiocarbonate Containing Compounds, Polymers, and Copolymers, and Polyurethanes and Urethane Acrylics Made Therefrom LUBRIZOL ADVANCED MATERIALS, INC. (US) 2012-07-05 US claimed
EP-2272884-A2 Hydroxyl-terminated thiocarbonate containing compounds, polymers, and copolymers, and polyurethanes and urethane acrylics made therefrom Lubrizol Advanced Materials, Inc. (US) 2011-01-12 EP claimed
EP-2272885-A2 Hydroxyl-terminated thiocarbonate containing compounds, polymers, and copolymers, and polyurethanes and urethane acrylics made therefrom Lubrizol Advanced Materials, Inc. (US) 2011-01-12 EP claimed
EP-2270061-A2 Hydroxyl-terminated thiocarbonate containing compounds, polymers, and copolymers, and polyurethanes and urethane acrylics made therefrom Lubrizol Advanced Materials, Inc. (US) 2011-01-05 EP claimed
US-20090312496-A1 Hydroxyl-Terminated Thiocarbonate Containing Compounds, Polymers, and Copolymers, and Polyurethanes and Urethane Acrylics Made Therefrom LAI JOHN TA-YUAN 2009-12-17 US claimed
US-20080050995-A1 Hydroxyl-Terminated Thiocarbonate Containing Compounds, Polymers, and Copolymers, and Polyurethanes and Urethane Acrylics Made Therefrom LUBRIZOL ADVANCED MATERIALS, INC. 2008-02-28 US claimed
EP-1786848-A1 POLYURETHANES AND URETHANE ACRYLICS MADE FROM HYDROXYL-TERMINATED THIOCARBONATE CONTAINING COMPOUNDS Noveon, Inc. (US) 2007-05-23 EP claimed
EP-1773905-A1 HYDROXYL-TERMINATED THIOCARBONATE CONTAINING COMPOUNDS, POLYMERS, AND COPOLYMERS, AND POLYURETHANES AND URETHANE ACRYLICS MADE THEREFROM Noveon, Inc. (US) 2007-04-18 EP claimed
WO-2006020116-A1 HYDROXYL-TERMINATED THIOCARBONATE CONTAINING COMPOUNDS, POLYMERS, AND COPOLYMERS, AND POLYURETHANES AND URETHANE ACRYLICS MADE THEREFROM NOVEON, INC. (US) 2006-02-23 WO claimed
WO-2006020281-A1 POLYURETHANES AND URETHANE ACRYLICS MADE FROM HYDROXYL-TERMINATED THIOCARBONATE CONTAINING COMPOUNDS NOVEON, INC. (US) 2006-02-23 WO claimed
US-20050009999-A1 Hydroxyl-terminated thiocarbonate containing compounds, polymers, and copolymers, and polyurethanes and urethane acrylics made therefrom LUBRIZOL ADVANCED MATERIALS, INC. 2005-01-13 US claimed
US-20250179263-A1 (POLY)ESTER AND (POLY)AMIDE COMPOSITIONS, METHOD FOR MODIFYING (POLY)ESTERS OR (POLY)AMIDES AND CATALYST THEREFOR FRIEDRICH-SCHILLER-UNIVERSITÄT JENA (DE) 2025-06-05 US disclosed
WO-2023160767-A1 (POLY)ESTER AND (POLY)AMIDE COMPOSITIONS, METHOD FOR MODIFYING (POLY)ESTERS OR (POLY)AMIDES AND CATALYST THEREFOR FRIEDRICH-SCHILLER-UNIVERSITÄT JENA (DE) 2023-08-31 WO disclosed
US-8709543-B2 Hydroxyl-terminated thiocarbonate containing compounds, polymers, and copolymers, and polyurethanes and urethane acrylics made therefrom LUBRIZOL ADVANCED MATERIALS, INC. (US) 2014-04-29 US disclosed
WO-2006020116-A1 HYDROXYL-TERMINATED THIOCARBONATE CONTAINING COMPOUNDS, POLYMERS, AND COPOLYMERS, AND POLYURETHANES AND URETHANE ACRYLICS MADE THEREFROM NOVEON, INC. (US) 2006-02-23 WO disclosed
WO-2006020281-A1 POLYURETHANES AND URETHANE ACRYLICS MADE FROM HYDROXYL-TERMINATED THIOCARBONATE CONTAINING COMPOUNDS NOVEON, INC. (US) 2006-02-23 WO disclosed
US-20050009999-A1 Hydroxyl-terminated thiocarbonate containing compounds, polymers, and copolymers, and polyurethanes and urethane acrylics made therefrom LUBRIZOL ADVANCED MATERIALS, INC. 2005-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120171914-A1 Hydroxyl-Terminated Thiocarbonate Containing Compounds, Polymers, and Copolymers, and Polyurethanes and Urethane Acrylics Made Therefrom ALKBH3, HAAO, BHMT2 ALDH1A1 931/4885TSHR 3660/4885
US-20090312496-A1 Hydroxyl-Terminated Thiocarbonate Containing Compounds, Polymers, and Copolymers, and Polyurethanes and Urethane Acrylics Made Therefrom ALKBH3, BHMT2, ALKBH2 ALDH1A1 190/4885TSHR 2857/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.