Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.58 |
| ▸ | CTSK | P43235 | 2/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | CTSS | P25774 | 1/20 | 0.50 |
| ▸ | ACACB | O00763 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.44 |
| ▸ | GRN | P28799 | 1/20 | 0.44 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18722285 | 0.84 | MMP9 (0.55) | CTSKGRNSORT1MMP9MMP8 | |
| SCHEMBL17530042 | 0.84 | MMP9 (0.55) | CTSKGRNSORT1MMP9MMP8 | |
| SCHEMBL17530041 | 0.84 | MMP9 (0.55) | CTSKGRNSORT1MMP9MMP8 | |
| SCHEMBL20853655 | 0.76 | FPR2 (0.66) | FPR2CTSKCTSLCTSBCTSS | |
| SCHEMBL1410991 | 0.75 | HDAC1 (0.49) | CTSKALDH1A1MMP9MMP8MMP14 | |
| SCHEMBL19712560 | 0.75 | LMNA (0.48) | CTSKALDH1A1LMNA | |
| SCHEMBL1414854 | 0.75 | LMNA (0.48) | CTSKALDH1A1LMNA | |
| SCHEMBL1410988 | 0.75 | HDAC1 (0.49) | CTSKALDH1A1MMP9MMP8MMP14 | |
| SCHEMBL1411215 | 0.75 | LMNA (0.48) | CTSKALDH1A1LMNA | |
| SCHEMBL1411220 | 0.75 | LMNA (0.48) | CTSKALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998054123-A1 | SUBSTITUTED PEPTIDYLAMINE CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1998-12-03 | — | — | WO | claimed |