Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.36 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.36 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | PSMB1 | P20618 | 3/20 | 0.35 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7275517 | 0.95 | SIGMAR1 (0.43) | SIGMAR1LTA4HSSTR5PSMB5PSMB8 | |
| SCHEMBL7283476 | 0.91 | SIGMAR1 (0.45) | SIGMAR1NPSR1 | |
| SCHEMBL7274358 | 0.91 | SIGMAR1 (0.44) | SIGMAR1NPSR1 | |
| SCHEMBL7282368 | 0.89 | SIGMAR1 (0.44) | SIGMAR1NPSR1 | |
| SCHEMBL7280624 | 0.88 | SIGMAR1 (0.45) | SIGMAR1ALDH1A1 | |
| SCHEMBL7275258 | 0.87 | CA12 (0.41) | SIGMAR1 | |
| SCHEMBL7274234 | 0.86 | SIGMAR1 (0.44) | SIGMAR1LTA4HSSTR5PSMB5PSMB8 | |
| SCHEMBL7272287 | 0.86 | SIGMAR1 (0.42) | SIGMAR1NPSR1 | |
| SCHEMBL7281590 | 0.85 | SIGMAR1 (0.44) | SIGMAR1ACACBNPSR1 | |
| SCHEMBL7274557 | 0.83 | SIGMAR1 (0.44) | SIGMAR1ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |