Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7368854 | 0.93 | KCNH2 (0.35) | LTA4HKCNH2HRH3ESR1HTR2C | |
| SCHEMBL7372480 | 0.88 | BACE1 (0.45) | LTA4HKCNH2HRH3 | |
| SCHEMBL7447534 | 0.87 | HRH3 (0.37) | LTA4HKCNH2HRH3ESR1ESR2 | |
| SCHEMBL7368529 | 0.84 | HRH3 (0.47) | LTA4HKCNH2HRH3ESR1SLC6A4 | |
| SCHEMBL7373580 | 0.82 | KDM4E (0.45) | KCNH2HRH3ESR1CHKAESR2 | |
| SCHEMBL7371832 | 0.80 | SIGMAR1 (0.40) | KCNH2HRH3SLC6A4KDM4EALDH1A1 | |
| SCHEMBL7371794 | 0.79 | KDM4E (0.40) | LTA4HKDM4EALDH1A1 | |
| SCHEMBL7373311 | 0.78 | ALDH1A1 (0.40) | ESR1ESR2KDM4EALDH1A1SIGMAR1 | |
| SCHEMBL7369101 | 0.78 | ALDH1A1 (0.40) | ESR1ESR2KDM4EALDH1A1 | |
| SCHEMBL7373846 | 0.77 | ACP1 (0.38) | KCNH2HRH3KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994859-A1 | COMPOUNDS | Astra Aktiebolag (publ) (SE) | 2000-04-26 | — | — | EP | claimed |
| WO-1999001437-A1 | COMPOUNDS | ASTRA AKTIEBOLAG (PUBL) (SE) | 1999-01-14 | — | — | WO | claimed |