Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8363347 | 0.92 | MEN1 (0.59) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7368949 | 0.81 | ITGB3 (0.50) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL20329333 | 0.79 | SMPD1 (0.59) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7363019 | 0.79 | KMT2A (0.45) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL31174375 | 0.78 | ALDH1A1 (0.58) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL30100625 | 0.77 | SMN1; SMN2 (0.67) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL28848865 | 0.77 | SMN1; SMN2 (0.67) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL30100607 | 0.77 | SMN1; SMN2 (0.60) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL20328290 | 0.77 | SMPD1 (0.59) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL20328346 | 0.76 | SMPD1 (0.58) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0767792-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-11-20 | — | — | EP | disclosed |
| US-5977101-A | Benzimidazoles/Imidazoles Linked to a Fibrinogen Receptor Antagonist Template Having Vitronectin Receptor Antagonist Activity | SMITHKLINE BEECHAM CORPORATION (US) | 1999-11-02 | — | — | US | disclosed |
| EP-0767792-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-04-16 | — | — | EP | disclosed |
| WO-1996000730-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-01-11 | — | — | WO | disclosed |