Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.59 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | GABRP | O00591 | 1/20 | 0.44 |
| ▸ | GABRD | O14764 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.44 |
| ▸ | GABRE | P78334 | 1/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.44 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.44 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8879157 | 0.80 | MAOB (0.53) | KDM4EGAAGFEREGFRFGFR2 | |
| SCHEMBL7367851 | 0.79 | LRRK2 (0.58) | IMPDH2IMPDH1GABRPGABRDGABRA1 | |
| SCHEMBL7185783 | 0.79 | EGFR (0.53) | IMPDH2IMPDH1GABRPGABRDGABRA1 | |
| SCHEMBL2542670 | 0.77 | KDM4E (0.53) | KDM4EGAAALDH1A1LRRK2PRKCI | |
| SCHEMBL91366 | 0.76 | IMPDH2 (1.00) | IMPDH2IMPDH1GAAGABRPGABRD | |
| SCHEMBL30389000 | 0.76 | IMPDH2 (1.00) | IMPDH2IMPDH1GAAGABRPGABRD | |
| Hydrochloric Acid SCHEMBL27803164 | 0.75 | IMPDH2 (0.96) | IMPDH2IMPDH1GAAGABRPGABRD | |
| SCHEMBL28194905 | 0.75 | IMPDH2 (0.96) | IMPDH2IMPDH1GAAGABRPGABRD | |
| SCHEMBL2542673 | 0.74 | KDM4E (0.53) | KDM4EGAAALDH1A1LRRK2PRKCI | |
| SCHEMBL8548736 | 0.73 | FGFR2 (0.55) | EGFRPRKCQPRKCDFGFR2FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688809-A | 5-heteroarylindole derivatives | PFIZER INC. (US) | 1997-11-18 | — | — | US | disclosed |
| WO-1995021836-A1 | 5-HETEROARYLINDOLE DERIVATIVES AS BENZODIAZEPINE RECEPTOR SITE AGONISTS AND ANTAGONISTS | PFIZER INC. (US) | 1995-08-17 | — | — | WO | disclosed |