Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.38 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.35 |
| ▸ | RBP4 | P02753 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7364619 | 0.75 | BTK (0.37) | HTR2AHTR2CTEAD1TEAD3BTK | |
| SCHEMBL7444511 | 0.72 | PARP14 (0.36) | HTR2AHTR2CBTKPARP14PARP1 | |
| SCHEMBL7360351 | 0.70 | PARP14 (0.40) | TEAD1PARP14GRIN2BPARP1 | |
| SCHEMBL7364168 | 0.70 | PRSS1 (0.40) | TEAD1TEAD3PARP14 | |
| SCHEMBL6979526 | 0.70 | POLB (0.52) | SYKPARP1 | |
| SCHEMBL31678664 | 0.69 | PARP1 (0.46) | ROCK2SYKPARP1 | |
| SCHEMBL22583344 | 0.69 | PARP1 (0.46) | ROCK2SYKPARP1 | |
| SCHEMBL7365153 | 0.68 | LMNA (0.36) | TEAD1TEAD3CYP2C9CYP2C19HTR2B | |
| SCHEMBL14334209 | 0.68 | IRAK4 (0.49) | TEAD1TEAD3ROCK2PARP1 | |
| SCHEMBL7083112 | 0.67 | PARP1 (0.47) | SYKPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997046553-A1 | THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1997-12-11 | — | — | WO | disclosed |