Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 3/20 | 0.36 |
| ▸ | BTK | Q06187 | 3/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 3/20 | 0.33 |
| ▸ | JAK2 | O60674 | 2/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.33 |
| ▸ | GPR183 | P32249 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7364619 | 0.85 | BTK (0.37) | PARP14BTKF2PRSS1PRSS2 | |
| SCHEMBL4096182 | 0.78 | HTR2A (0.40) | PARP14BTKTNKSPARP1HTR2A | |
| SCHEMBL7365919 | 0.76 | GRIN2D (0.36) | PARP14BTKTNKSPARP1HTR2A | |
| SCHEMBL7360351 | 0.74 | PARP14 (0.40) | PARP14TNKSPARP1EPHX2 | |
| SCHEMBL3140703 | 0.73 | PARP1 (0.43) | PARP14BTKTNKSPARP1HTR2A | |
| SCHEMBL7369282 | 0.72 | HTR2A (0.38) | PARP14BTKPARP1HTR2AHTR2C | |
| SCHEMBL7444516 | 0.68 | DPP4 (0.45) | — | |
| SCHEMBL7364168 | 0.68 | PRSS1 (0.40) | PARP14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7365153 | 0.66 | LMNA (0.36) | PARP14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL3127933 | 0.66 | BCHE (0.44) | BTKPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997046553-A1 | THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1997-12-11 | — | — | WO | disclosed |