Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD3 | Q9NY59 | 12/20 | 0.52 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.49 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | BRAF | P15056 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370040 | 0.88 | TUBB4A (0.48) | SMPD3MAPTTP53BRAFKDM4E | |
| SCHEMBL27674785 | 0.85 | CYP11B1 (0.48) | MAPTTP53BRAFKDM4EALDH1A1 | |
| SCHEMBL7369283 | 0.83 | NOX1 (0.59) | SMPD3NOX1BRAFKDM4EALDH1A1 | |
| SCHEMBL7366807 | 0.82 | NPY5R (0.59) | MAPTKDM4EMEN1ALDH1A1HPGD | |
| SCHEMBL7369244 | 0.81 | GAA (0.55) | SMPD3NOX1MAPTBRAFKDM4E | |
| SCHEMBL7373890 | 0.80 | PDGFRB (0.44) | KDM4ENPY5RTUBB4ATUBBTUBA3C | |
| SCHEMBL7371101 | 0.79 | PDGFRB (0.44) | NPY5RTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7375046 | 0.79 | NPY5R (0.55) | MAPTBRAFKDM4EALDH1A1HPGD | |
| SCHEMBL22291217 | 0.79 | SMPD3 (0.76) | SMPD3NOX1AMY1AMAPTTP53 | |
| SCHEMBL7370258 | 0.78 | MKNK1 (0.46) | NPY5RTUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822805-A | ANTIINFLAMMATORY AGENTS, CARDIOTONIC AGENTS, ANTIPLATELET AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| EP-0257897-A1 | Imidazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |