Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.64 |
| ▸ | HTR2B | P41595 | 3/20 | 0.64 |
| ▸ | HTR2A | P28223 | 2/20 | 0.64 |
| ▸ | HTR1A | P08908 | 2/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7365906 | 0.88 | HTR2C (0.64) | HTR2CHTR2BHTR2AHTR1AADRA2A | |
| SCHEMBL7368923 | 0.87 | HTR2A (0.49) | HTR2CHTR2BHTR2AHTR1A | |
| SCHEMBL7370137 | 0.87 | HTR2C (0.63) | HTR2CHTR2BHTR2AHTR1AADRA2A | |
| SCHEMBL7400843 | 0.81 | HTR2C (0.62) | HTR2CHTR2BHTR2AHTR1AADRA2A | |
| SCHEMBL7365853 | 0.80 | HTR4 (0.65) | HTR2CHTR2BHTR2AHTR1AADRA2A | |
| SCHEMBL7364199 | 0.79 | HTR2C (0.64) | HTR2CHTR2BHTR2AHTR1AADRA2A | |
| SCHEMBL7370424 | 0.78 | HTR3E (0.56) | HTR2CHTR2BHTR2AHTR1AHTR3A | |
| SCHEMBL7365939 | 0.78 | HTR3E (0.54) | HTR2CHTR2BHTR2AHTR1AHTR3A | |
| SCHEMBL7362880 | 0.78 | HTR2C (0.66) | HTR2CHTR2BHTR2AHTR1AADRA2A | |
| SCHEMBL7364193 | 0.77 | HTR3E (0.56) | HTR2CHTR2BHTR2AHTR1AHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001014381-A1 | ETHER DERIVATIVES OF PYRROLO[1,2-A]QUINOXALINES, METHOD FOR PRODUCING THEM AND THEIR USE IN THERAPY | UNIVERSITE DE CAEN BASSE-NORMANDIE (FR) | 2001-03-01 | — | — | WO | disclosed |