Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.62 |
| ▸ | HTR2B | P41595 | 4/20 | 0.62 |
| ▸ | HTR1A | P08908 | 2/20 | 0.62 |
| ▸ | HTR3A | P46098 | 2/20 | 0.62 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.62 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.62 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.62 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.62 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.62 |
| ▸ | HTR2A | P28223 | 2/20 | 0.59 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7364199 | 0.93 | HTR2C (0.64) | HTR2CHTR2BHTR1AHTR3AADRA2A | |
| SCHEMBL7370424 | 0.90 | HTR3E (0.56) | HTR2CHTR2BHTR1AHTR3AHTR2A | |
| SCHEMBL7365853 | 0.89 | HTR4 (0.65) | HTR2CHTR2BHTR1AHTR3AADRA2A | |
| SCHEMBL7362880 | 0.83 | HTR2C (0.66) | HTR2CHTR2BHTR1AHTR3AADRA2A | |
| SCHEMBL7369399 | 0.81 | HTR2C (0.64) | HTR2CHTR2BHTR1AHTR3AADRA2A | |
| SCHEMBL7370137 | 0.80 | HTR2C (0.63) | HTR2CHTR2BHTR1AHTR3AADRA2A | |
| SCHEMBL7364193 | 0.78 | HTR3E (0.56) | HTR2CHTR2BHTR1AHTR3AHTR2A | |
| SCHEMBL7365939 | 0.75 | HTR3E (0.54) | HTR2CHTR2BHTR1AHTR3AHTR2A | |
| SCHEMBL7362654 | 0.75 | HTR2A (0.50) | HTR2CHTR2BHTR1AHTR2A | |
| SCHEMBL7365419 | 0.74 | HTR2A (0.49) | HTR2CHTR2BHTR1AHTR2AHTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001014381-A1 | ETHER DERIVATIVES OF PYRROLO[1,2-A]QUINOXALINES, METHOD FOR PRODUCING THEM AND THEIR USE IN THERAPY | UNIVERSITE DE CAEN BASSE-NORMANDIE (FR) | 2001-03-01 | — | — | WO | disclosed |