Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28856012 | 0.69 | HSD17B10 (0.50) | HSD17B10CHEK1LMNAAKT1MAPK1 | |
| SCHEMBL24129893 | 0.68 | HSD17B10 (0.56) | HSD17B10CHEK1LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL11267628 | 0.68 | HSD17B10 (0.49) | HSD17B10CHEK1LMNAAKT1MAPK1 | |
| SCHEMBL11838994 | 0.67 | LMNA (0.59) | HSD17B10CHEK1LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL4743261 | 0.67 | HSD17B10 (0.69) | HSD17B10LMNAMAPK1SMN1; SMN2RAB9A | |
| SCHEMBL11224907 | 0.67 | HSD17B10 (0.48) | HSD17B10CHEK1LMNAAKT1MAPK1 | |
| SCHEMBL3382220 | 0.67 | HSD17B10 (0.66) | HSD17B10CHEK1LMNAAKT1SMN1; SMN2 | |
| SCHEMBL1218749 | 0.67 | HSD17B10 (1.00) | HSD17B10CHEK1LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL31529600 | 0.67 | HSD17B10 (1.00) | HSD17B10CHEK1LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL15311825 | 0.67 | AKT1 (0.57) | HSD17B10CHEK1LMNAAKT1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999026941-A1 | SUBSTITUTED AMIDINOARYL DERIVATIVES AND THEIR USE AS ANTICOAGULANTS | AXYS PHARMACEUTICALS, INC. (US) | 1999-06-03 | — | — | WO | disclosed |