SCHEMBL4743261

SCHEMBL4743261

CCOC(=O)Cc1nc2ccccc2c(=O)[nH]1

nearest known ligand 0.69

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.69
GAA P10253 1/20 0.66
TNKS2 Q9H2K2 2/20 0.62
LMNA P02545 3/20 0.58
KDM4E B2RXH2 2/20 0.58
KMT2A Q03164 2/20 0.57
PARP1 P09874 3/20 0.57
PARP2 Q9UGN5 1/20 0.57
MAPT P10636 2/20 0.54
RAB9A P51151 1/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
ALDH1A1 P00352 2/20 0.53
USP2 O75604 2/20 0.52
TSHR P16473 1/20 0.52
MAPK1 P28482 1/20 0.52
PDE10A Q9Y233 1/20 0.51
MEN1 O00255 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3558037 0.86 KDM4E (0.66) HSD17B10TNKS2LMNAKDM4EKMT2A
SCHEMBL11548717 0.86 HSD17B10 (0.61) HSD17B10GAATNKS2LMNAKDM4E
SCHEMBL10084487 0.84 HSD17B10 (0.55) HSD17B10GAALMNAKDM4EKMT2A
SCHEMBL24802486 0.82 HSD17B10 (0.53) HSD17B10GAALMNAKDM4EMAPT
SCHEMBL1218749 0.82 HSD17B10 (1.00) HSD17B10GAALMNAKDM4EKMT2A
SCHEMBL31529600 0.82 HSD17B10 (1.00) HSD17B10GAALMNAKDM4EKMT2A
SCHEMBL18824358 0.79 PARP1 (0.64) TNKS2LMNAKDM4EKMT2APARP1
SCHEMBL14021530 0.78 RAB9A (0.63) GAATNKS2LMNAKDM4EPARP1
SCHEMBL16181940 0.78 ALDH1A1 (0.70) GAALMNAKDM4EKMT2AMAPT
SCHEMBL30782682 0.78 BRD4 (0.55) GAATNKS2LMNAKDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8177861-B2 AZO pigment, pigment dispersion containing the AZO pigment, and coloring composition FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-8177861-B2 AZO pigment, pigment dispersion containing the AZO pigment, and coloring composition FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-20110021764-A1 AZO PIGMENT, PIGMENT DISPERSION CONTAINING THE AZO PIGMENT, AND COLORING COMPOSITION FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed
US-20110021764-A1 AZO PIGMENT, PIGMENT DISPERSION CONTAINING THE AZO PIGMENT, AND COLORING COMPOSITION FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed
US-4870000-A Color photograhic recording material containing a coupler which releases a photographically active compound AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) 1989-09-26 US disclosed