Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28856012 | 0.81 | HSD17B10 (0.50) | HSD17B10CA12CA1CA2CA9 | |
| SCHEMBL24129893 | 0.72 | HSD17B10 (0.56) | HSD17B10CHEK1LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL443306 | 0.71 | CA12 (0.56) | HSD17B10CA12CA1CA2CA9 | |
| SCHEMBL24129892 | 0.70 | HSD17B10 (0.41) | HSD17B10CA12CA1CA2CA9 | |
| SCHEMBL874500 | 0.70 | LMNA (0.48) | HSD17B10CA12CA1CA2CA9 | |
| SCHEMBL8625346 | 0.70 | HSD17B10 (0.47) | HSD17B10CA12CA1CA2CA9 | |
| SCHEMBL25914348 | 0.69 | RAB9A (0.61) | HSD17B10LMNAMAPK1RAB9AKDM4E | |
| SCHEMBL688262 | 0.69 | CA12 (0.53) | HSD17B10CA12CA1CA2CA9 | |
| SCHEMBL11530302 | 0.69 | CA12 (0.49) | HSD17B10CA12CA1CA2CA9 | |
| SCHEMBL11223443 | 0.69 | CA12 (0.49) | HSD17B10CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323676-A | Process for preparing cephalosporins | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-04-06 | — | — | US | disclosed |
| US-4308381-A | Cephem compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-12-29 | — | — | US | disclosed |
| US-4245088-A | Novel 3-acyloxymethyl-cephem compounds useful as intermediates for preparing cephalosporin antibiotics | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-01-13 | — | — | US | disclosed |