Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 9/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | GCGR | P47871 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7369410 | 0.85 | PDE5A (0.58) | CYP11B1CYP11B2PDE5ANPY5RPOLB | |
| SCHEMBL7366257 | 0.83 | PDE5A (0.56) | CYP11B1CYP11B2PDE5ANPY5RPDE4A | |
| SCHEMBL27692933 | 0.81 | CYP11B1 (0.50) | CYP11B1CYP11B2NPY5RKDM4ELDHA | |
| SCHEMBL7370892 | 0.81 | NPY5R (0.57) | CYP11B1CYP11B2NPY5RKDM4ELDHA | |
| SCHEMBL7374350 | 0.80 | MAOB (0.46) | CYP11B1CYP11B2PDE5ANPY5RPDE4A | |
| SCHEMBL7370832 | 0.79 | CYP11B1 (0.52) | CYP11B1CYP11B2NPY5RKDM4ELDHA | |
| SCHEMBL7376655 | 0.79 | MGAM (0.52) | CYP11B1CYP11B2PDE5ANPY5RKDM4E | |
| SCHEMBL7369697 | 0.79 | NPY5R (0.54) | CYP11B1CYP11B2MAPK14NPY5RKDM4E | |
| SCHEMBL7369715 | 0.79 | CYP11B1 (0.52) | CYP11B1CYP11B2MAPK14NPY5RKDM4E | |
| SCHEMBL7369268 | 0.77 | PDE5A (0.47) | CYP11B1CYP11B2PDE5AGCGRNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822805-A | ANTIINFLAMMATORY AGENTS, CARDIOTONIC AGENTS, ANTIPLATELET AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| EP-0257897-A1 | Imidazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |