Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 6/20 | 0.57 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.55 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | AHR | P35869 | 1/20 | 0.50 |
| ▸ | KIT | P10721 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.43 |
| ▸ | TEK | Q02763 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7369697 | 0.86 | NPY5R (0.54) | NPY5RCYP11B1CYP11B2NPC1HPGD | |
| SCHEMBL7369715 | 0.86 | CYP11B1 (0.52) | NPY5RCYP11B1CYP11B2NPC1HPGD | |
| SCHEMBL7376655 | 0.86 | MGAM (0.52) | NPY5RCYP11B1CYP11B2NPC1HPGD | |
| SCHEMBL7370832 | 0.86 | CYP11B1 (0.52) | NPY5RCYP11B1CYP11B2NPC1HPGD | |
| SCHEMBL7372656 | 0.84 | ALOX5 (0.50) | NPY5RCYP11B1CYP11B2NPC1HPGD | |
| SCHEMBL27692933 | 0.84 | CYP11B1 (0.50) | NPY5RCYP11B1CYP11B2NPC1HPGD | |
| Hydrochloric Acid SCHEMBL7369410 | 0.83 | PDE5A (0.58) | NPY5RCYP11B1CYP11B2SMN1; SMN2ALDH1A1 | |
| SCHEMBL7372422 | 0.83 | NPY5R (0.57) | NPY5RCYP11B1CYP11B2NPC1HPGD | |
| SCHEMBL7374881 | 0.81 | PRKCA (0.44) | NPY5RCYP11B1CYP11B2NPC1HPGD | |
| SCHEMBL7366257 | 0.81 | PDE5A (0.56) | NPY5RCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822805-A | ANTIINFLAMMATORY AGENTS, CARDIOTONIC AGENTS, ANTIPLATELET AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| EP-0257897-A1 | Imidazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |