Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7363786 | 0.94 | TSHR (0.41) | ALDH1A1L3MBTL1CYP3A4TSHRMAPK1 | |
| SCHEMBL8992625 | 0.75 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1CYP3A4TSHRMAPK1 | |
| SCHEMBL7364482 | 0.74 | LNPEP (0.37) | CYP3A4NPC1RAB9AMEN1KMT2A | |
| SCHEMBL3350413 | 0.71 | ESR1 (0.41) | ALDH1A1L3MBTL1TDP1ESR1NPC1 | |
| SCHEMBL10436017 | 0.69 | TSHR (0.49) | ALDH1A1L3MBTL1CYP3A4TSHRMAPK1 | |
| SCHEMBL3351101 | 0.69 | KDM4E (0.45) | ALDH1A1L3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL30029282 | 0.69 | KDM4E (0.45) | ALDH1A1L3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL23250562 | 0.68 | ESR1 (0.67) | ALDH1A1L3MBTL1CYP3A4TSHRMAPK1 | |
| SCHEMBL3355550 | 0.68 | LMNA (0.42) | ALDH1A1L3MBTL1TDP1ESR1MEN1 | |
| SCHEMBL3853627 | 0.68 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1CYP3A4TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920307-A2 | DERIVATES FROM BISARYLTETRACARBONACID, AND PHARMARCEUTICAL PRODUCT CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1999-06-09 | — | — | EP | disclosed |
| WO-1998006386-A2 | DERIVATES FROM BISARYLTETRACARBONACID, AND PHARMARCEUTICAL PRODUCT CONTAINING THEM | ROCHE DIAGNOSTICS GMBH (DE) | 1998-02-19 | — | — | WO | disclosed |