Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | WNT1 | P04628 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.35 |
| ▸ | CFD | P00746 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.34 |
| ▸ | KRAS | P01116 | 3/20 | 0.34 |
| ▸ | ELANE | P08246 | 2/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7341547 | 0.96 | GSK3B (0.36) | GSK3BWNT1DYRK1AHTR4CFD | |
| SCHEMBL7349903 | 0.90 | ELANE (0.45) | GSK3BWNT1DYRK1AHTR4CNR1 | |
| SCHEMBL8818127 | 0.86 | GSK3B (0.37) | GSK3BWNT1DYRK1AHTR4CNR1 | |
| SCHEMBL8819437 | 0.85 | ITGB3 (0.38) | GSK3BCFDCNR1MAP3K14ELANE | |
| SCHEMBL7350998 | 0.84 | GPR119 (0.39) | GSK3BWNT1DYRK1AHTR4CNR1 | |
| SCHEMBL7349538 | 0.81 | GPR119 (0.38) | — | |
| SCHEMBL8820147 | 0.81 | CNR2 (0.38) | GSK3BWNT1DYRK1AHTR4 | |
| SCHEMBL7351896 | 0.80 | GPR119 (0.37) | CNR1 | |
| SCHEMBL7412242 | 0.80 | GPR119 (0.37) | CNR1 | |
| SCHEMBL17023809 | 0.80 | CFD (0.41) | CFDMAP3K14KRASELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1222153-A | Piperidine acetic acid derivatives and their use in the treatment of thrombotic disorders | GLAXO GROUP LTD (GB) | 1999-07-07 | — | — | CN | disclosed |
| EP-0912555-A1 | PIPERIDINE ACETIC ACID DERIVATIVES AND THEIR USE IN THE TREATMENT OF THROMBOTIC DISORDERS | GLAXO GROUP LIMITED (GB) | 1999-05-06 | — | — | EP | disclosed |
| WO-1997049699-A1 | PIPERIDINE ACETIC ACID DERIVATIVES AND THEIR USE IN THE TREATMENT OF THROMBOTIC DISORDERS | GLAXO GROUP LIMITED (GB) | 1997-12-31 | — | — | WO | disclosed |
| WO-1997049698-A1 | PIPERIDINE ACETIC ACID DERIVATIVES AND THEIR USE IN THE TREATMENT OF THROMBOTIC DISORDERS | GLAXO GROUP LIMITED (GB) | 1997-12-31 | — | — | WO | disclosed |