Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 16/20 | 0.54 |
| ▸ | THRB | P10828 | 16/20 | 0.54 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL328377 | 0.86 | THRB (0.67) | THRATHRB | |
| SCHEMBL12949905 | 0.85 | THRA (0.51) | THRATHRB | |
| SCHEMBL7372730 | 0.79 | THRB (0.80) | THRATHRB | |
| SCHEMBL3911899 | 0.78 | IGF1R (0.52) | THRATHRBSLC28A3 | |
| SCHEMBL27666398 | 0.77 | THRA (0.48) | THRATHRB | |
| SCHEMBL28643551 | 0.77 | THRB (0.64) | THRATHRB | |
| SCHEMBL20920805 | 0.77 | IGF1R (0.53) | THRATHRB | |
| SCHEMBL1860686 | 0.76 | CNR1 (0.60) | THRATHRB | |
| SCHEMBL25773018 | 0.76 | THRB (0.71) | THRATHRB | |
| SCHEMBL25983465 | 0.74 | THRB (0.53) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991618-A4 | SELECTIVE THYROID HORMONE ANALOGS | UNIV CALIFORNIA (US) | 2000-09-27 | — | — | EP | disclosed |
| EP-0991618-A1 | SELECTIVE THYROID HORMONE ANALOGS | The Regents of the University of California (US) | 2000-04-12 | — | — | EP | disclosed |
| WO-1998057919-A1 | SELECTIVE THYROID HORMONE ANALOGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-12-23 | — | — | WO | disclosed |