Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 19/20 | 0.67 |
| ▸ | THRA | P10827 | 18/20 | 0.67 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25773018 | 0.90 | THRB (0.71) | THRBTHRAESR1ESR2 | |
| SCHEMBL25983465 | 0.89 | THRB (0.53) | THRBTHRAESR1ESR2 | |
| SCHEMBL4963467 | 0.88 | THRB (0.64) | THRBTHRAESR1ESR2 | |
| SCHEMBL27703134 | 0.88 | THRB (0.64) | THRBTHRAESR1ESR2 | |
| SCHEMBL1457668 | 0.88 | THRB (0.67) | THRBTHRAESR1ESR2 | |
| SCHEMBL27702889 | 0.88 | THRB (0.64) | THRBTHRAESR1ESR2 | |
| SCHEMBL12824810 | 0.86 | THRB (0.67) | THRBTHRAESR1ESR2 | |
| SCHEMBL7369671 | 0.86 | THRA (0.54) | THRBTHRA | |
| SCHEMBL10064689 | 0.85 | THRB (0.69) | THRBTHRA | |
| SCHEMBL4196757 | 0.85 | THRB (0.61) | THRBTHRAESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119431265-A | Compound as thyroid hormone receptor agonist | 南京瑞捷医药科技有限公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-113474335-B | Compounds and their use as thyroid hormone receptor agonists | 南京瑞捷医药科技有限公司 | 2024-12-03 | — | — | CN | disclosed |
| CN-106414718-A | SC-beta cells and compositions and methods for producing the same | 哈佛学院校长同事会 | 2017-02-15 | — | — | CN | disclosed |
| CN-105579577-A | SC-beta cells and compositions and methods for producing the same | HARVARD COLLEGE | 2016-05-11 | — | — | CN | disclosed |
| CN-104940126-A | Controlled-release otic structure modulating and innate immune system modulating compositions and methods for the treatment of otic disorders | OTONOMY INC | 2015-09-30 | — | — | CN | disclosed |
| CN-102105133-B | Controlled release otic structure modulating and innate immune system modulating compositions and methods of treating otic disorders | OTONOMY INC | 2015-06-17 | — | — | CN | disclosed |
| CN-104491864-A | Controlled Release Antimicrobial Compositions And Methods For The Treatment Of Otic Disorders | OTONOMY INC | 2015-04-08 | — | — | CN | disclosed |
| CN-102014957-B | Otic formulations for the treatment of otic diseases and conditions | OTONOMY INC | 2014-12-10 | — | — | CN | disclosed |
| EP-2567959-A1 | 6-(4-Hydroxy-phenyl)-3-styryl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors | SANOFI (FR) | 2013-03-13 | — | — | EP | disclosed |
| EP-2428516-A1 | Novel phosphorus-containing thyromimetics | Metabasis Therapeutics, Inc. (US) | 2012-03-14 | — | — | EP | disclosed |
| EP-1891080-A2 | NOVEL PHOSPHORUS-CONTAINING THYROMIMETICS | Metabasis Therapeutics, Inc. (US) | 2008-02-27 | — | — | EP | disclosed |
| EP-1890768-A2 | NOVEL PHOSPHINIC ACID-CONTAINING THYROMIMETICS | Metabasis Therapeutics, Inc. (US) | 2008-02-27 | — | — | EP | disclosed |
| CN-1882327-A | Novel phosphorus-containing thyromimetics | METABASIS THERAPEUTICS INC (US) | 2006-12-20 | — | — | CN | disclosed |
| WO-2006128056-A2 | NOVEL PHOSPHINIC ACID-CONTAINING THYROMIMETICS | METABASIS THERAPEUTICS, INC. (US) | 2006-11-30 | — | — | WO | disclosed |
| WO-2006128055-A2 | NOVEL PHOSPHORUS-CONTAINING THYROMIMETICS | METABASIS THERAPEUTICS, INC. (US) | 2006-11-30 | — | — | WO | disclosed |
| EP-0991618-B1 | SELECTIVE THYROID HORMONE ANALOGS | UNIV CALIFORNIA (US) | 2003-11-12 | — | — | EP | disclosed |
| EP-0991618-A4 | SELECTIVE THYROID HORMONE ANALOGS | UNIV CALIFORNIA (US) | 2000-09-27 | — | — | EP | disclosed |
| EP-0991618-A1 | SELECTIVE THYROID HORMONE ANALOGS | The Regents of the University of California (US) | 2000-04-12 | — | — | EP | disclosed |
| US-5883294-A | THYROID HORMONE AGONIST | THE REGEANTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-03-16 | — | — | US | disclosed |
| WO-1998057919-A1 | SELECTIVE THYROID HORMONE ANALOGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-12-23 | — | — | WO | disclosed |