SCHEMBL7369701

SCHEMBL7369701

COc1cccc(CSCc2cccc(OC)c2)c1

nearest known ligand 0.70

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.70
TAAR1 Q96RJ0 3/20 0.58
IDO1 P14902 2/20 0.58
AGXT P21549 2/20 0.58
CHRM2 P08172 2/20 0.55
CHRM1 P11229 2/20 0.55
CHRM3 P20309 2/20 0.55
CMA1 P23946 1/20 0.53
POLB P06746 1/20 0.53
MAOB P27338 1/20 0.52
SIGMAR1 Q99720 1/20 0.51
AOC3 Q16853 1/20 0.51
LPO P22079 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23927284 0.88 CYP1A2 (0.60) CYP1A2TAAR1IDO1AGXTCHRM2
SCHEMBL1145638 0.86 CYP1A2 (0.58) CYP1A2TAAR1IDO1AGXTCHRM2
SCHEMBL15023273 0.86 TAAR1 (0.62) CYP1A2TAAR1IDO1AGXTCHRM2
SCHEMBL1145636 0.84 CYP1A2 (0.57) CYP1A2TAAR1IDO1AGXTCHRM2
SCHEMBL24188255 0.84 CYP1A2 (0.57) CYP1A2TAAR1IDO1AGXTCHRM2
SCHEMBL6788100 0.83 CYP1A2 (1.00) CYP1A2POLB
SCHEMBL6011732 0.82 TAAR1 (0.67) CYP1A2TAAR1IDO1AGXTCHRM2
SCHEMBL12125567 0.81 TAAR1 (0.59) CYP1A2TAAR1IDO1AGXTCHRM2
SCHEMBL723511 0.80 TAAR1 (0.77) TAAR1IDO1AGXTCHRM2CHRM1
SCHEMBL2099512 0.80 CHRM2 (0.66) TAAR1IDO1AGXTCHRM2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113563357-B Compound for organic photoelectric device, composition for organic photoelectric device, and display device 三星SDI株式会社 2024-09-10 CN disclosed
EP-4139281-B1 SULFUR EXTRUSION FROM DISULFIDES BY CARBENES UNIV HEIDELBERG (DE) 2024-05-08 EP disclosed
US-20230151054-A1 SULFUR EXTRUSION FROM DISULFIDES BY CARBENES Universität Heidelberg (DE) 2023-05-18 US disclosed
US-20230151054-A1 SULFUR EXTRUSION FROM DISULFIDES BY CARBENES Universität Heidelberg (DE) 2023-05-18 US disclosed
US-20230151054-A1 SULFUR EXTRUSION FROM DISULFIDES BY CARBENES Universität Heidelberg (DE) 2023-05-18 US disclosed
CN-115141814-B Application of 4-hydroxyacetophenone monooxygenase 江南大学 2023-05-05 CN disclosed
EP-4139281-A1 SULFUR EXTRUSION FROM DISULFIDES BY CARBENES Universität Heidelberg (DE) 2023-03-01 EP disclosed
CN-112321469-B Synthetic method of dibenzyl sulfide 成都理工大学 2022-07-12 CN disclosed
CN-111517902-B Aerobic oxidation system containing sulfinic acid, sulfonic acid or derivatives thereof and photo-oxidation promoting method thereof 清华大学 2022-06-14 CN disclosed
CN-111559976-B Synthetic method of heteroaryl thioether 扬州大学 2022-05-13 CN disclosed
EP-3901135-A1 SULFUR EXTRUSION FROM DISULFIDES BY CARBENES Universität Heidelberg (DE) 2021-10-27 EP disclosed
CN-112321469-A Synthetic method of dibenzyl sulfide 成都理工大学 2021-02-05 CN disclosed
CN-111559976-A Synthetic method of heteroaryl thioether 扬州大学 2020-08-21 CN disclosed
CN-107004768-B Organic semiconductor composition containing a liquid medium 巴斯夫欧洲公司 2020-08-21 CN disclosed
CN-111517902-A Aerobic oxidation system containing sulfinic acid, sulfonic acid or derivatives thereof and photo-oxidation promoting method thereof 清华大学 2020-08-11 CN disclosed
CN-108689894-B Synthesis method of green high-conversion-number sulfoxide compound 南阳师范学院 2020-06-09 CN disclosed
US-6380218-B1 FOR THERAPY OF RESPIRATORY, ALLERGIC, AND INFLAMMATORY DISORDERS COMPRISING ASTHMA, CHRONIC OBSTRUCTIVE PULMONARY DISEASE, ACUTE RESPIRATORY DISEASE SYNDROME, PULMONARY HYPERSENSITIVITY, AND ALLERGIC RHINITIS IN A MAMMAL PFIZER INC 2002-04-30 US disclosed
EP-0971894-A1 NICOTINAMIDE DERIVATIVES Pfizer Products Inc. (US) 2000-01-19 EP disclosed
WO-1998045268-A1 NICOTINAMIDE DERIVATIVES PFIZER PRODUCTS INC. (US) 1998-10-15 WO disclosed
US-5470854-A Antiestrogens SCHERING AKTIENGESELLSCHAFT (DE) 1995-11-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230151054-A1 SULFUR EXTRUSION FROM DISULFIDES BY CARBENES TST, CBS, CTH CYP1A2 1247/4885TAAR1 3595/4885IDO1 1812/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.