Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | GLA | P06280 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29374375 | 0.78 | PSMB5 (0.65) | ALDH1A1KDM4EL3MBTL1TDP1HPGD | |
| SCHEMBL3359420 | 0.78 | PSMB5 (0.65) | ALDH1A1KDM4EL3MBTL1TDP1HPGD | |
| SCHEMBL296131 | 0.77 | NPC1 (0.46) | ALDH1A1KDM4EHPGDMAPTGLA | |
| SCHEMBL8574353 | 0.76 | KMT2A (0.74) | ALDH1A1KDM4EL3MBTL1TDP1HPGD | |
| SCHEMBL30644242 | 0.76 | KDM4E (0.53) | ALDH1A1KDM4EL3MBTL1TDP1HPGD | |
| SCHEMBL10816949 | 0.76 | KDM4E (0.53) | ALDH1A1KDM4EL3MBTL1TDP1HPGD | |
| SCHEMBL28632440 | 0.76 | TDP1 (0.55) | ALDH1A1KDM4EL3MBTL1TDP1HPGD | |
| SCHEMBL7071941 | 0.76 | PSMB5 (0.71) | ALDH1A1KDM4EL3MBTL1TDP1HPGD | |
| SCHEMBL31054483 | 0.76 | PSMB5 (0.63) | ALDH1A1KDM4EL3MBTL1TDP1HPGD | |
| SCHEMBL5258959 | 0.76 | ALDH1A1 (0.51) | ALDH1A1KDM4EL3MBTL1TDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995001343-A1 | PYRIDAZINONE DERIVATIVES WITH PHARMACEUTICAL ACTIVITY | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1995-01-12 | — | — | WO | disclosed |