Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.46 |
| ▸ | RAB9A | P51151 | 9/20 | 0.46 |
| ▸ | AR | P10275 | 9/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11614311 | 0.78 | AR (0.49) | NPC1RAB9AARCYP3A4CYP1A2 | |
| SCHEMBL7369914 | 0.77 | ALDH1A1 (0.51) | NPC1RAB9AALDH1A1HPGDMAPT | |
| SCHEMBL12853993 | 0.76 | PTGS2 (0.57) | NPC1RAB9AARCYP3A4CYP1A2 | |
| SCHEMBL21037673 | 0.76 | AR (0.50) | NPC1RAB9AARCYP3A4CYP1A2 | |
| SCHEMBL31038123 | 0.76 | AR (0.55) | NPC1RAB9AARCYP3A4CYP1A2 | |
| SCHEMBL21215650 | 0.76 | ALDH1A1 (0.52) | NPC1RAB9AARCYP3A4CYP1A2 | |
| SCHEMBL29374931 | 0.75 | RAB9A (0.64) | NPC1RAB9AARCYP3A4CYP1A2 | |
| SCHEMBL170196 | 0.75 | RAB9A (0.64) | NPC1RAB9AARCYP3A4CYP1A2 | |
| SCHEMBL13408682 | 0.74 | AR (0.49) | NPC1RAB9AARCYP3A4CYP1A2 | |
| Bromide SCHEMBL20502170 | 0.74 | PTGS2 (0.56) | NPC1RAB9AARCYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948627-B1 | NOVEL DUAL PEPTIDASE INHIBITORS AS PRODRUGS FOR THE THERAPY OF INFLAMMATORY AND OTHER DISORDERS | IMTM GMBH (DE) | 2012-03-14 | — | — | EP | disclosed |
| EP-2178527-A1 | METHOD FOR ACTIVATING REGULATORY T-CELLS | IMTM GmbH (DE) | 2010-04-28 | — | — | EP | disclosed |
| WO-2009024348-A1 | METHOD FOR ACTIVATING REGULATORY T-CELLS | IMTM GMBH (DE) | 2009-02-26 | — | — | WO | disclosed |