SCHEMBL737005

SCHEMBL737005

[CH2]Cc1ccccc1C(N)(N)CC

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.32
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31
PNMT P11086 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15271 0.83 GABRA1 (0.43) IDO1GABRA1GABRB2
SCHEMBL1322725 0.74 ALDH1A1 (0.44) IDO1GABRA1GABRB2
SCHEMBL11431192 0.72 ACHE (0.39) GABRA1GABRB2
Phthalic Acid SCHEMBL18546103 0.72 ALDH1A1 (0.45) GABRA1GABRB2
SCHEMBL6672227 0.71 TSHR (0.52) IDO1GABRA1GABRB2
SCHEMBL8523009 0.71 TAAR1 (0.31) IDO1
SCHEMBL37758 0.71 TAAR1 (0.34) IDO1
SCHEMBL18528701 0.71 TAAR1 (0.31) IDO1
SCHEMBL11081926 0.71 GABRA1 (0.43) GABRA1GABRB2
SCHEMBL30498855 0.71 GABRA1 (0.43) GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5948419-A AQUEOUS EMULSION POLYMERIC BINDER; SILANE COUPLING AGENT THE DUMAIS COMPANIES, L.L.C. (US) 1999-09-07 US claimed
JP-10010894-A None JP disclosed
EP-3551003-A1 SHOE SOLES, COMPOSITIONS, AND METHODS OF MAKING THE SAME Cooper-Standard Automotive, Inc. (US) 2019-10-16 EP disclosed
EP-3551453-A1 ROOFING MEMBRANES, COMPOSITIONS, AND METHODS OF MAKING THE SAME Cooper-Standard Automotive, Inc. (US) 2019-10-16 EP disclosed
EP-3551452-A1 HOSES, COMPOSITIONS, AND METHODS OF MAKING THE SAME Cooper-Standard Automotive, Inc. (US) 2019-10-16 EP disclosed
EP-3551715-A1 MICRODENSE SEALS, COMPOSITIONS, AND METHODS OF MAKING THE SAME Cooper-Standard Automotive, Inc. (US) 2019-10-16 EP disclosed
EP-3551712-A1 COMBINED SEALS, COMPOSITIONS, AND METHODS OF MAKING THE SAME Cooper-Standard Automotive, Inc. (US) 2019-10-16 EP disclosed
EP-3551713-A1 STATIC SEALS, COMPOSITIONS, AND METHODS OF MAKING THE SAME Cooper-Standard Automotive, Inc. (US) 2019-10-16 EP disclosed
EP-3551714-A1 DYNAMIC SEALS, COMPOSITIONS, AND METHODS OF MAKING THE SAME Cooper-Standard Automotive, Inc. (US) 2019-10-16 EP disclosed
WO-2018107115-A9 DYNAMIC SEALS, COMPOSITIONS, AND METHODS OF MAKING THE SAME COOPER-STANDARD AUTOMOTIVE INC. (US) 2018-09-20 WO disclosed
EP-0850196-B1 PROCESS FOR THE PRODUCTION OF ORGANOFUNCTIONALISED AEROGELS CABOT CORP (US) 2002-06-26 EP disclosed
WO-2002030483-A1 MOISTURE CURABLE BALLOON MATERIALS SCIMED LIFE SYSTEMS, INC. (US) 2002-04-18 WO disclosed
US-6191173-B1 GELLING WATER GLASS BY POLYCONDENSATION; TREATING WITH BIFUNCTIONAL ORGANIC COMPOUND LINKING COMPOUND TO AEROGEL; DRYING WITH RETENTION OF GEL STRUCTURE HOECHST RESEARCH TECHNOLOGY DEUTSCHLAND GMBH (DE) 2001-02-20 US disclosed
US-5948419-A AQUEOUS EMULSION POLYMERIC BINDER; SILANE COUPLING AGENT THE DUMAIS COMPANIES, L.L.C. (US) 1999-09-07 US disclosed
EP-0850196-A1 PROCESS FOR THE PRODUCTION OF ORGANOFUNCTIONALISED AEROGELS Hoechst Research & Technology Deutschland GmbH & Co. KG (DE) 1998-07-01 EP disclosed
JP-H1010894-A FUSER SYSTEM MEMBER XEROX CORP 1998-01-16 JP disclosed
WO-1997010177-A1 PROCESS FOR THE PRODUCTION OF ORGANOFUNCTIONALISED AEROGELS HOECHST RESEARCH & TECHNOLOGY DEUTSCHLAND GMBH & CO. KG (DE) 1997-03-20 WO disclosed
WO-1995021262-A1 PROCESS FOR SOLID PHASE GLYCOPEPTIDE SYNTHESIS THE SCRIPPS RESEARCH INSTITUTE (US) 1995-08-10 WO disclosed
US-5369017-A Process for solid phase glycopeptide synthesis THE SCRIPPS RESEARCH INSTITUTE (US) 1994-11-29 US disclosed
EP-0396156-A1 Method of manufacturing a membrane for an electrochemical sensor MILES INC. (US) 1990-11-07 EP disclosed