Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 8/20 | 0.45 |
| ▸ | NPC1 | O15118 | 7/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7399011 | 0.99 | LTA4H (0.46) | LTA4HHRH3RAB9ANPC1CASP3 | |
| Hydrochloric Acid SCHEMBL7366186 | 0.93 | LTA4H (0.47) | LTA4HHRH3RAB9ANPC1CASP3 | |
| Hydrochloric Acid SCHEMBL7367440 | 0.88 | LTA4H (0.46) | LTA4HHRH3 | |
| Hydrochloric Acid SCHEMBL7369765 | 0.80 | LTA4H (0.51) | LTA4HHRH3RAB9ANPC1CASP3 | |
| SCHEMBL7440022 | 0.79 | LTA4H (0.48) | LTA4HHRH3RAB9ANPC1HTT | |
| Hydrochloric Acid SCHEMBL7447695 | 0.78 | LTA4H (0.47) | LTA4HHRH3RAB9ANPC1HTT | |
| Bromide SCHEMBL10316873 | 0.74 | ALDH1A1 (0.40) | LMNAALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL3227805 | 0.73 | MEN1 (0.41) | LTA4HKDM4EALDH1A1MEN1KMT2A | |
| Bromide SCHEMBL12004496 | 0.72 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1 | |
| SCHEMBL339813 | 0.69 | LMNA (0.82) | LTA4HRAB9ALMNACYP1A2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625981-A1 | AZABICYCLO COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-11-30 | — | — | EP | claimed |
| WO-1993015080-A1 | AZABICYCLO COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1993-08-05 | — | — | WO | claimed |