Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 7/20 | 0.53 |
| ▸ | MMP9 | P14780 | 6/20 | 0.53 |
| ▸ | MMP8 | P22894 | 4/20 | 0.53 |
| ▸ | MMP1 | P03956 | 7/20 | 0.47 |
| ▸ | FCER2 | P06734 | 3/20 | 0.47 |
| ▸ | MMP7 | P09237 | 3/20 | 0.46 |
| ▸ | MMP12 | P39900 | 2/20 | 0.46 |
| ▸ | MMP13 | P45452 | 2/20 | 0.46 |
| ▸ | MMP3 | P08254 | 3/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.41 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370874 | 0.85 | MMP2 (0.53) | MMP2MMP9MMP8MMP1FCER2 | |
| SCHEMBL7370265 | 0.82 | MMP1 (0.57) | MMP2MMP9MMP8MMP1FCER2 | |
| SCHEMBL12304173 | 0.79 | NPC1 (0.56) | MMP2MMP9MMP8NPC1RAB9A | |
| SCHEMBL7416043 | 0.78 | NPC1 (0.51) | MMP2MMP9MMP8NPC1RAB9A | |
| SCHEMBL4634157 | 0.78 | MMP2 (0.60) | MMP2MMP9MMP8MMP1FCER2 | |
| SCHEMBL9713814 | 0.78 | MMP2 (0.60) | MMP2MMP9MMP8MMP1FCER2 | |
| SCHEMBL7410539 | 0.77 | LTA4H (0.58) | LTA4HNPC1RAB9A | |
| SCHEMBL7367696 | 0.77 | MMP1 (0.69) | MMP2MMP9MMP8MMP1FCER2 | |
| SCHEMBL5552820 | 0.77 | MMP1 (0.62) | MMP2MMP9MMP8MMP1FCER2 | |
| SCHEMBL7374482 | 0.77 | MMP1 (0.72) | MMP2MMP9MMP8MMP1FCER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0231081-B1 | HYDROXAMIC ACIDS | ICI AMERICAS INC. (US) | 1993-03-17 | — | — | EP | disclosed |
| US-4771038-A | Hydroxamic acids | ICI AMERICAS INC. (US) | 1988-09-13 | — | — | US | disclosed |
| EP-0231081-A2 | Hydroxamic acids | ICI AMERICAS INC. (US) | 1987-08-05 | — | — | EP | disclosed |