Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | TERT | O14746 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5884397 | 0.81 | DRD3 (0.57) | ALDH1A1POLBMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL11722763 | 0.79 | DRD3 (0.59) | ALDH1A1MAPTKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL7373085 | 0.78 | SHMT2 (0.49) | ALDH1A1KMT2ALMNA | |
| SCHEMBL11713412 | 0.78 | HRH3 (0.56) | — | |
| SCHEMBL3874659 | 0.77 | HRH3 (0.53) | — | |
| SCHEMBL8017307 | 0.76 | HDAC1 (0.44) | — | |
| Hydrochloric Acid SCHEMBL3876019 | 0.76 | HRH3 (0.52) | — | |
| SCHEMBL7374886 | 0.74 | HDAC3 (0.54) | — | |
| SCHEMBL23886464 | 0.73 | SIGMAR1 (0.59) | ALDH1A1POLBKMT2ALMNAGAA | |
| SCHEMBL13661591 | 0.73 | MAPT (0.70) | ALDH1A1POLBMAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999026932-A1 | BY AMIDINO GROUP SUBSTITUTED HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTICOAGULANTS | AXYS PHARMACEUTICALS, INC. (US) | 1999-06-03 | — | — | WO | disclosed |