Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 20/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 15/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 5/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7373085 | 0.76 | SHMT2 (0.49) | HDAC1HDAC3HDAC2HDAC10HDAC6 | |
| SCHEMBL7370267 | 0.76 | ALDH1A1 (0.51) | — | |
| SCHEMBL7374886 | 0.75 | HDAC3 (0.54) | HDAC1HDAC3HDAC2HDAC10HDAC6 | |
| SCHEMBL2973683 | 0.70 | HDAC3 (0.47) | HDAC1HDAC3HDAC2HDAC10HDAC6 | |
| SCHEMBL7366151 | 0.69 | CA12 (0.62) | HDAC1HDAC3HDAC2HDAC10HDAC6 | |
| SCHEMBL6201094 | 0.67 | MAPT (0.52) | HDAC1HDAC3HDAC2HDAC10HDAC6 | |
| SCHEMBL9320885 | 0.66 | KAT2B (0.54) | HDAC1HDAC3HDAC2HDAC10HDAC6 | |
| SCHEMBL3871501 | 0.66 | HDAC1 (0.55) | HDAC1HDAC3HDAC2HDAC10HDAC6 | |
| SCHEMBL13728016 | 0.65 | ALDH1A1 (0.64) | HDAC1HDAC3HDAC2HDAC10HDAC6 | |
| SCHEMBL7375160 | 0.64 | KDM4E (0.49) | HDAC1HDAC3HDAC2HDAC10HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056435-A1 | DYEING METHOD USING AN ALIPHATIC CATIONIC AMINE AND A ALDEHYDE OR KETONE OR QUINONE OR DI-IMINO-ISOINDOLINE OR 3-AMINO-ISOINDOLONE DERIVATIVES | L'OREAL (FR) | 2000-12-06 | — | — | EP | disclosed |
| WO-2000038641-A1 | DYEING METHOD USING AN ALIPHATIC CATIONIC AMINE AND A ALDEHYDE OR KETONE OR QUINONE OR DI-IMINO-ISOINDOLINE OR 3-AMINO-ISOINDOLONE DERIVATIVES | L'OREAL (FR) | 2000-07-06 | — | — | WO | disclosed |