Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.37 |
| ▸ | CTSS | P25774 | 4/20 | 0.37 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 3/20 | 0.34 |
| ▸ | REN | P00797 | 7/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | MMP9 | P14780 | 2/20 | 0.34 |
| ▸ | ANPEP | P15144 | 2/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | LAP3 | P28838 | 1/20 | 0.34 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.34 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.34 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.34 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.34 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.34 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.34 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7343512 | 1.00 | CTSK (0.37) | CTSKCTSSPSMB1PSMB5PSMB2 | |
| SCHEMBL9557890 | 1.00 | CTSK (0.37) | CTSKCTSSPSMB1PSMB5PSMB2 | |
| SCHEMBL7344316 | 0.89 | CTSK (0.36) | CTSKCTSSPSMB1PSMB5PSMB2 | |
| SCHEMBL7344921 | 0.86 | REN (0.39) | CTSKCTSSREN | |
| SCHEMBL7337274 | 0.85 | PSMB1 (0.49) | CTSKCTSSPSMB1PSMB5PSMB2 | |
| SCHEMBL7336544 | 0.84 | CTSK (0.38) | CTSKCTSSCTSLRENCTSB | |
| SCHEMBL7344678 | 0.81 | CTSK (0.42) | CTSKCTSSPSMB5CTSLREN | |
| SCHEMBL7338842 | 0.78 | CTSK (0.39) | CTSKCTSSCTSLRENCTSB | |
| SCHEMBL7344724 | 0.76 | REN (0.36) | CTSKREN | |
| SCHEMBL7343275 | 0.72 | CTSK (0.33) | CTSKCTSSCTSLREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5416117-A | Protease inhibitor | MITSUBISHI KASEI CORPORATION (JP) | 1995-05-16 | — | — | US | disclosed |
| EP-0520427-B1 | Cyclopropenone derivatives | MITSUBISHI CHEM IND (JP) | 1994-12-14 | — | — | EP | disclosed |
| US-5328909-A | Protease inhibitors | MITSUBISHI KASEI CORPORATION (JP) | 1994-07-12 | — | — | US | disclosed |
| EP-0520427-A1 | Cyclopropenone derivatives | Mitsubishi Chemical Corporation (JP) | 1992-12-30 | — | — | EP | disclosed |