Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 17/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 17/20 | 0.49 |
| ▸ | PREP | P48147 | 1/20 | 0.39 |
| ▸ | FAP | Q12884 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | FLT4 | P35916 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7931567 | 1.00 | ITGB3 (0.49) | ITGB3ITGA2BPREPFAPDPP8 | |
| SCHEMBL7931569 | 0.90 | ITGB3 (0.42) | ITGB3ITGA2BPREPFAPDPP8 | |
| Trifluoroacetic Acid SCHEMBL7931550 | 0.88 | ITGB3 (0.48) | ITGB3ITGA2BROCK2ROCK1 | |
| Trifluoroacetic Acid SCHEMBL7931542 | 0.88 | ITGB3 (0.48) | ITGB3ITGA2BROCK2ROCK1 | |
| SCHEMBL7372733 | 0.87 | ITGB3 (0.43) | ITGB3ITGA2BPREPFAPDPP8 | |
| SCHEMBL7372729 | 0.87 | ITGB3 (0.43) | ITGB3ITGA2BPREPFAPDPP8 | |
| SCHEMBL7372732 | 0.87 | ITGB3 (0.43) | ITGB3ITGA2BPREPFAPDPP8 | |
| Trifluoroacetic Acid SCHEMBL7366990 | 0.84 | ITGB3 (0.48) | ITGB3ITGA2B | |
| Trifluoroacetic Acid SCHEMBL7924867 | 0.84 | ITGB3 (0.48) | ITGB3ITGA2B | |
| SCHEMBL7370446 | 0.81 | PREP (0.38) | ITGB3ITGA2BPREPFAPDPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242600-B1 | ANTIISCHEMIC AGENTS, ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-0970071-A1 | 2-PEPERAZINONE-1-ACETIC ACID DERIVATIVES AND THEIR USE | Takeda Chemical Industries, Ltd. (JP) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998039324-A1 | 2-PEPERAZINONE-1-ACETIC ACID DERIVATIVES AND THEIR USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-11 | — | — | WO | disclosed |