Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 1/20 | 0.38 |
| ▸ | FAP | Q12884 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 12/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 8/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.33 |
| ▸ | PRKG1 | Q13976 | 3/20 | 0.33 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.33 |
| ▸ | CDK1 | P06493 | 2/20 | 0.33 |
| ▸ | PRKACA | P17612 | 2/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | GSK3A | P49840 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 2/20 | 0.33 |
| ▸ | PRKX | P51817 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7366992 | 0.84 | ALDH1A1 (0.34) | ALDH1A1MAPTITGB3ITGA2BLMNA | |
| SCHEMBL7931569 | 0.84 | ITGB3 (0.42) | PREPFAPDPP8DPP9ROCK2 | |
| Trifluoroacetic Acid SCHEMBL7370443 | 0.81 | ITGB3 (0.49) | PREPFAPDPP8DPP9ROCK2 | |
| Trifluoroacetic Acid SCHEMBL7931567 | 0.81 | ITGB3 (0.49) | PREPFAPDPP8DPP9ROCK2 | |
| SCHEMBL7372733 | 0.78 | ITGB3 (0.43) | PREPFAPDPP8DPP9ROCK2 | |
| SCHEMBL7372729 | 0.78 | ITGB3 (0.43) | PREPFAPDPP8DPP9ROCK2 | |
| SCHEMBL7372732 | 0.78 | ITGB3 (0.43) | PREPFAPDPP8DPP9ROCK2 | |
| SCHEMBL7364293 | 0.76 | DPP8 (0.41) | FAPDPP8ROCK2ALDH1A1ITGB3 | |
| SCHEMBL7374179 | 0.72 | ITGB3 (0.40) | ROCK2ROCK1ITGB3ITGA2BPRKG1 | |
| Trifluoroacetic Acid SCHEMBL7931550 | 0.70 | ITGB3 (0.48) | ROCK2ROCK1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0970071-A1 | 2-PEPERAZINONE-1-ACETIC ACID DERIVATIVES AND THEIR USE | Takeda Chemical Industries, Ltd. (JP) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998039324-A1 | 2-PEPERAZINONE-1-ACETIC ACID DERIVATIVES AND THEIR USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-11 | — | — | WO | disclosed |