Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 18/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 18/20 | 0.48 |
| ▸ | ITGA2 | P17301 | 2/20 | 0.47 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7924867 | 1.00 | ITGB3 (0.48) | ITGB3ITGA2BITGA2CCR1LMNA | |
| SCHEMBL7924872 | 0.90 | ITGB3 (0.40) | ITGB3ITGA2BITGA2CCR1LMNA | |
| Trifluoroacetic Acid SCHEMBL7931567 | 0.84 | ITGB3 (0.49) | ITGB3ITGA2B | |
| Trifluoroacetic Acid SCHEMBL7370443 | 0.84 | ITGB3 (0.49) | ITGB3ITGA2B | |
| SCHEMBL7924876 | 0.84 | ITGB3 (0.49) | ITGB3ITGA2BITGA2 | |
| SCHEMBL7924865 | 0.84 | ITGB3 (0.49) | ITGB3ITGA2BITGA2 | |
| SCHEMBL7924873 | 0.84 | ITGB3 (0.49) | ITGB3ITGA2BITGA2 | |
| SCHEMBL7366992 | 0.82 | ALDH1A1 (0.34) | ITGB3ITGA2BITGA2CCR1LMNA | |
| SCHEMBL7931569 | 0.74 | ITGB3 (0.42) | ITGB3ITGA2BLMNA | |
| Trifluoroacetic Acid SCHEMBL7931550 | 0.72 | ITGB3 (0.48) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242600-B1 | ANTIISCHEMIC AGENTS, ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-0970071-A1 | 2-PEPERAZINONE-1-ACETIC ACID DERIVATIVES AND THEIR USE | Takeda Chemical Industries, Ltd. (JP) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998039324-A1 | 2-PEPERAZINONE-1-ACETIC ACID DERIVATIVES AND THEIR USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-11 | — | — | WO | disclosed |