Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TDO2 | P48775 | 9/20 | 0.49 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.48 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2300936 | 0.81 | ASH1L (0.52) | ASH1LTDO2IMPDH2NR4A2MAPK1 | |
| SCHEMBL24196091 | 0.81 | ASH1L (0.55) | ASH1LIDO1 | |
| SCHEMBL24025940 | 0.79 | HTR1D (0.51) | MEN1NPC1LMNAHPGDRAB9A | |
| SCHEMBL25043136 | 0.79 | ASH1L (0.59) | ASH1LMEN1NPC1KMT2ATDO2 | |
| SCHEMBL20937890 | 0.77 | CDC7 (0.64) | MAPK1 | |
| SCHEMBL27613441 | 0.77 | ASH1L (0.60) | ASH1LSMN1; SMN2TDO2IMPDH2NR4A2 | |
| SCHEMBL23649189 | 0.76 | ASH1L (0.63) | ASH1LTDO2IMPDH2NR4A2MAPK1 | |
| SCHEMBL29824426 | 0.76 | ASH1L (0.63) | ASH1LTDO2IMPDH2NR4A2MAPK1 | |
| SCHEMBL6586643 | 0.76 | ASH1L (0.59) | ASH1LMEN1LMNAKMT2ATDO2 | |
| SCHEMBL30695578 | 0.76 | ASH1L (0.59) | ASH1LMEN1LMNAKMT2ATDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722436-A4 | MERCAPTOSULFIDE METALLOPROTEINASE INHIBITORS | UNIV FLORIDA STATE (US) | 1996-11-20 | — | — | EP | disclosed |
| EP-0722436-A1 | MERCAPTOSULFIDE METALLOPROTEINASE INHIBITORS | FLORIDA STATE UNIVERSITY (US) | 1996-07-24 | — | — | EP | disclosed |
| WO-1995009833-A1 | MERCAPTOSULFIDE METALLOPROTEINASE INHIBITORS | FLORIDA STATE UNIVERSITY (US) | 1995-04-13 | — | — | WO | disclosed |