Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.72 |
| ▸ | MMP3 | P08254 | 1/20 | 0.72 |
| ▸ | FNTA | P49354 | 1/20 | 0.47 |
| ▸ | FNTB | P49356 | 1/20 | 0.47 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 8/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 8/20 | 0.46 |
| ▸ | ELANE | P08246 | 3/20 | 0.44 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370806 | 1.00 | MMP1 (0.72) | MMP1MMP3FNTAFNTBPGGT1B | |
| SCHEMBL7399018 | 1.00 | MMP1 (0.72) | MMP1MMP3FNTAFNTBPGGT1B | |
| SCHEMBL7403306 | 0.84 | MMP1 (1.00) | MMP1MMP3ANPEP | |
| SCHEMBL7403305 | 0.84 | MMP1 (1.00) | MMP1MMP3ANPEP | |
| SCHEMBL7405291 | 0.84 | MMP1 (1.00) | MMP1MMP3ANPEP | |
| SCHEMBL7407555 | 0.84 | MMP1 (1.00) | MMP1MMP3ANPEP | |
| SCHEMBL17724815 | 0.81 | MMP1 (0.48) | MMP1MMP3TAS1R3TAS1R1ELANE | |
| SCHEMBL13912399 | 0.77 | ANPEP (0.47) | MMP1MMP3TAS1R3TAS1R1ELANE | |
| SCHEMBL12621365 | 0.77 | ANPEP (0.47) | MMP1MMP3TAS1R3TAS1R1ELANE | |
| SCHEMBL6241209 | 0.75 | TAS1R3 (0.68) | TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0925303-B1 | PHOSPHINIC ACID AMIDES AS MATRIX METALLOPROTEASE INHIBITORS | PROCTER & GAMBLE (US) | 2002-10-23 | — | — | EP | disclosed |
| EP-0925303-A1 | PHOSPHINIC ACID AMIDES AS MATRIX METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1999-06-30 | — | — | EP | disclosed |
| US-5830915-A | ORAL DISEASES; SKIN DISORDERS; ANTIINFLAMMATORY AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1998-11-03 | — | — | US | disclosed |
| WO-1998008853-A9 | PHOSPHINIC ACID AMIDES AS MATRIX METALLOPROTEASE INHIBITORS | — | 1998-08-06 | — | — | WO | disclosed |
| WO-1998008853-A1 | PHOSPHINIC ACID AMIDES AS MATRIX METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1998-03-05 | — | — | WO | disclosed |