Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 7/20 | 1.00 |
| ▸ | MMP3 | P08254 | 7/20 | 1.00 |
| ▸ | MMP9 | P14780 | 4/20 | 0.54 |
| ▸ | MMP7 | P09237 | 2/20 | 0.54 |
| ▸ | MMP8 | P22894 | 2/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.52 |
| ▸ | ANPEP | P15144 | 5/20 | 0.50 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7405291 | 1.00 | MMP1 (1.00) | MMP1MMP3MMP9MMP7MMP8 | |
| SCHEMBL7403306 | 1.00 | MMP1 (1.00) | MMP1MMP3MMP9MMP7MMP8 | |
| SCHEMBL7407555 | 1.00 | MMP1 (1.00) | MMP1MMP3MMP9MMP7MMP8 | |
| SCHEMBL7370803 | 0.84 | MMP1 (0.72) | MMP1MMP3ANPEP | |
| SCHEMBL7399018 | 0.84 | MMP1 (0.72) | MMP1MMP3ANPEP | |
| SCHEMBL7370806 | 0.84 | MMP1 (0.72) | MMP1MMP3ANPEP | |
| SCHEMBL8721568 | 0.74 | MMP3 (0.59) | MMP1MMP3MMP9MMP7MMP8 | |
| SCHEMBL8723456 | 0.73 | MMP1 (0.58) | MMP1MMP3MMP9MMP7MMP8 | |
| SCHEMBL8725721 | 0.73 | MMP1 (0.58) | MMP1MMP3MMP9MMP7MMP8 | |
| SCHEMBL11619882 | 0.71 | ANPEP (0.57) | MMP1MMP3MMP9MMP8ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0925303-B1 | PHOSPHINIC ACID AMIDES AS MATRIX METALLOPROTEASE INHIBITORS | PROCTER & GAMBLE (US) | 2002-10-23 | — | — | EP | claimed |
| EP-0925303-B1 | PHOSPHINIC ACID AMIDES AS MATRIX METALLOPROTEASE INHIBITORS | PROCTER & GAMBLE (US) | 2002-10-23 | — | — | EP | disclosed |
| EP-0925303-A1 | PHOSPHINIC ACID AMIDES AS MATRIX METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1999-06-30 | — | — | EP | disclosed |
| WO-1998008853-A9 | PHOSPHINIC ACID AMIDES AS MATRIX METALLOPROTEASE INHIBITORS | — | 1998-08-06 | — | — | WO | disclosed |
| WO-1998008853-A1 | PHOSPHINIC ACID AMIDES AS MATRIX METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1998-03-05 | — | — | WO | disclosed |