Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7365185 | 0.89 | CTRB1 (0.43) | ALDH1A1KMT2AL3MBTL1POLBPKM | |
| SCHEMBL7365769 | 0.84 | ALPI (0.46) | ALDH1A1LMNATP53SMN1; SMN2PKM | |
| SCHEMBL29131646 | 0.84 | ALPI (0.46) | ALDH1A1LMNATP53SMN1; SMN2PKM | |
| SCHEMBL28809664 | 0.81 | PPARG (0.46) | ALDH1A1GAANPC1KMT2ALMNA | |
| SCHEMBL4152418 | 0.81 | ALDH1A1 (0.44) | MMP8NPY1RNPY2RALDH1A1GAA | |
| SCHEMBL15805201 | 0.78 | ALDH1A1 (0.56) | MMP8NPY1RNPY2RALDH1A1GAA | |
| SCHEMBL21428971 | 0.77 | MMP8 (0.54) | MMP8NPY1RNPY2RALDH1A1GAA | |
| SCHEMBL27387902 | 0.76 | MMP8 (0.50) | MMP8NPY1RNPY2RALDH1A1GAA | |
| SCHEMBL27625790 | 0.76 | MMP8 (0.43) | MMP8NPY1RNPY2RALDH1A1GAA | |
| SCHEMBL5569701 | 0.76 | POLB (0.46) | ALDH1A1MEN1KMT2APOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001973-A1 | COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | Elan Pharmaceuticals, Inc. (US) | 2000-05-24 | — | — | EP | claimed |
| WO-1999006433-A1 | COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARMACEUTICALS, INC. (US) | 1999-02-11 | — | — | WO | claimed |