SCHEMBL737221

SCHEMBL737221

OB(O)Oc1cccc(C(F)(F)F)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.53
KDM4E B2RXH2 1/20 0.46
MAOB P27338 1/20 0.45
AOC3 Q16853 1/20 0.45
PPARG P37231 4/20 0.44
PPARA Q07869 1/20 0.44
CES2 O00748 1/20 0.44
TSHR P16473 1/20 0.44
MAPK1 P28482 1/20 0.44
MRGPRX4 Q96LA9 1/20 0.43
SLC6A2 P23975 1/20 0.43
SLC6A4 P31645 1/20 0.43
SLC6A3 Q01959 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
MAPT P10636 1/20 0.41
PRSS1 P07477 1/20 0.41
ACR P10323 1/20 0.41
HTR3E A5X5Y0 1/20 0.41
HTR3B O95264 1/20 0.41
HTR3A P46098 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8593767 0.89 MGLL (0.53) MGLLKDM4EMAOBAOC3PPARG
SCHEMBL5133335 0.86 MGLL (0.47) MGLLKDM4EMAOBAOC3PPARG
SCHEMBL1483908 0.84 MGLL (0.47) MGLLKDM4EMAOBAOC3PPARG
SCHEMBL31612146 0.84 MGLL (0.47) MGLLKDM4EMAOBAOC3PPARG
SCHEMBL30666619 0.81 MGLL (0.42) MGLLKDM4EMAOBAOC3PPARG
Benzene SCHEMBL28493930 0.80 IDO1 (0.40) MGLLPPARGPPARACES2TSHR
SCHEMBL466921 0.79 CES2 (0.41) MGLLCES2MAPTIDO1
SCHEMBL3982548 0.79 MAOB (0.44) MGLLKDM4EMAOBAOC3PPARG
SCHEMBL29718811 0.79 NR1H2 (0.37)
SCHEMBL28782372 0.79 NR1H2 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118336009-A Phenylboronic acid-based additive and electrolyte for lithium/carbon fluoride primary battery 上海大学 2024-07-12 CN claimed
CN-115928264-B Preparation method of continuous silicon carbide fiber containing metal in near-stoichiometric ratio 湖南泽睿新材料有限公司 2024-02-20 CN claimed
CN-117342907-A Method for preparing phenol by hydroxylation reaction of boric acid derivative in air under no-alkali condition without light catalyst 江西科技师范大学 2024-01-05 CN claimed
CN-117209367-A Fluorenyl bisphenol monomer and fluorenyl polyarylether resin, and preparation method and application thereof 大连理工大学 2023-12-12 CN claimed
CN-115928264-A Preparation method of metal-containing near-stoichiometric continuous silicon carbide fiber 湖南泽睿新材料有限公司 2023-04-07 CN claimed
CN-116283740-B Synthesis method of drug intermediate 上海添泽生物医药有限公司 2025-06-10 CN disclosed
CN-116730943-B Compound and medical application thereof 中国药科大学 2025-02-11 CN disclosed
WO-2024235209-A1 COMPOUND HAVING ANTI-TUMOR ACTIVITY, AND PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF 中国医学科学院药物研究所 2024-11-21 WO disclosed
CN-118336009-A Phenylboronic acid-based additive and electrolyte for lithium/carbon fluoride primary battery 上海大学 2024-07-12 CN disclosed
CN-113946103-B Dry film resist, method for manufacturing circuit wiring, input device, and display device 富士胶片株式会社 2024-05-07 CN disclosed
CN-115928264-B Preparation method of continuous silicon carbide fiber containing metal in near-stoichiometric ratio 湖南泽睿新材料有限公司 2024-02-20 CN disclosed
CN-115124485-B Sulfoxide-containing benzoxazole derivative, and preparation method and application thereof 中国医学科学院药物研究所 2023-12-15 CN disclosed
WO-2000037455-A1 BENZOTHIEPIN-ANILIDE DERIVATIVES, THEIR PRODUCTION AND THEIR USE FOR ANTAGONIZING CCR-5 TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2000-06-29 WO disclosed
WO-2000034249-A1 PROCESS FOR PREPARING PYRIDAZIN-3-ON DERIVATIVES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-06-15 WO disclosed
CN-1251523-A Sulfonamide derivatives LILLY CO ELI (US) 2000-04-26 CN disclosed
US-5877190-A PHOSPHODIESTERASE INHIBITOR ADIR ET COMPAGNIE (FR) 1999-03-02 US disclosed
WO-1998028262-A1 O-BENZYL OXIME ETHER DERIVATIVES AS PECTICIDES NOVARTIS AG (CH) 1998-07-02 WO disclosed
WO-1997001551-A1 PYRAZOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1997-01-16 WO disclosed
EP-0675118-A2 Biphenylderivatives, process for their preparation and their use as medicaments Eisai Co., Ltd. (JP) 1995-10-04 EP disclosed
CN-1072562-A HERBICIDAL BIPHENYLAMINE DERIVATIVES DU PONT (US) 1993-06-02 CN disclosed