Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | ACR | P10323 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8593767 | 0.90 | MGLL (0.53) | MGLLKDM4EMAOBAOC3PPARG | |
| SCHEMBL737221 | 0.86 | MGLL (0.53) | MGLLKDM4EMAOBAOC3PPARG | |
| SCHEMBL31612146 | 0.78 | MGLL (0.47) | MGLLKDM4EMAOBAOC3PPARG | |
| SCHEMBL4980059 | 0.78 | CA1 (0.36) | TSHRALDH1A1 | |
| SCHEMBL1483908 | 0.78 | MGLL (0.47) | MGLLKDM4EMAOBAOC3PPARG | |
| SCHEMBL28564005 | 0.74 | ALDH1A1 (0.39) | MGLLKDM4EPPARGPPARAMRGPRX4 | |
| SCHEMBL3982548 | 0.74 | MAOB (0.44) | MGLLKDM4EMAOBAOC3PPARG | |
| SCHEMBL28493928 | 0.72 | TRPV6 (0.42) | MGLLKDM4EPPARGPPARAMRGPRX4 | |
| SCHEMBL535445 | 0.72 | TSHR (0.48) | MGLLKDM4EMAOBAOC3PPARG | |
| SCHEMBL11527555 | 0.72 | KIF11 (0.51) | MGLLKDM4EMAOBAOC3PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919887-A2 | METHOD FOR ENANTIOSELECTIVE HYDROGENATION OF CHROMENES | Girindus America, Inc. (US) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007016423-A2 | METHOD FOR ENANTIOSELECTIVE HYDROGENATION OF CHROMENES | GIRINDUS AMERICA INC. (US) | 2007-02-08 | — | — | WO | disclosed |